You Searched For: 1-(2,6-Difluorophenyl)ethanol


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Supplier: AOBChem USA
Description: 1-(4-Chloro-2,6-difluorophenyl)ethanol ≥97%

Supplier: AOBChem USA
Description: 1-(2,6-Difluorophenyl)ethanol ≥95%

Catalog Number: (AAH32771-09)
Supplier: Thermo Scientific Chemicals
Description: 10g CAS: 87327-65-9, MDL: MFCD00274321

Supplier: AOBChem USA
Description: 1-(3,5-Dichloro-2,6-difluorophenyl)ethanol ≥95%

New Product

Supplier: AOBChem USA
Description: 1-(3,5-Dibromo-2,6-Difluorophenyl)ethanol ≥97%

Supplier: Ambeed
Description: 1-(2,6-Difluorophenyl)ethanol, Purity: 97%, CAS Number: 87327-65-9, Appearance: Colorless to yellow liquid, Storage: Sealed in dry, Room Temperature, Size: 1g

Supplier: AOBChem USA
Description: 1-(3-BROMO-26-DIFLUOROPHENYL)ETHANOL 5G

New Product

Supplier: AOBChem USA
Description: 1-(3-CHLORO-26-DIFLUOROPHENYL)ETHANOL 1G

New Product

Supplier: Ambeed
Description: 4-Bromo-2,6-difluoro-α-methylbenzyl alcohol 97%

Supplier: AOBChem USA
Description: 4-Bromo-2,6-difluoro-α-methylbenzyl alcohol ≥97%

Supplier: Adipogen
Description: VX745 is a selective inhibitor of p38alpha with an IC(50) of 10nM.

Supplier: Adipogen
Description: The kinases called p38 MAP kinases (MAPKs) are intracellular, soluble serine-threonine kinases which belong to a large family of proteins that include the extracellular regulated kinases (ERKs) and c-Jun N-terminal kinases (JNKs). So far four p38 isoforms have been identified, namely p38alpha, p38beta, p38gamma and p38delta, a.k.a. p38-alpha (MAPK14), -beta (MAPK11), -gamma (MAPK12 / ERK6), and -delta (MAPK13 / SAPK4). The ubiquitously expressed s p38alpha has been the most extensively studied and is believed to be the most physiologically relevant in the regulation of the inflammatory response. The role of the three other isoforms is not currently well understood, however their primary sites of expression are known. Similar to p38alpha, p38beta is also ubiquitously expressed, while p38gamma is expressed predominately in skeletal muscle and p38delta is expressed primarily in the lung, kidney, testis, small intestine and pancreas. The small molecule inhibitor VX-702 is a potent p38 kinase family inhibitor that has been studied for its effects on inflammation and the inflammatory response. VX-702 dose-dependently inhibited the production o IL-6, IL-1beta and TNFalpha (IC(50) = 59, 122 and 99ng/ml, respectively), and in anti-platelet aggregation assays, pre-incubation of platelets with VX-702 (1µM)completely or partially inhibited platelet agonist induced p38 activation (IC(50) = 4 to 20nM). More recently VX-702 has been studied as a potential treatment for rheumatoid arthritis (RA). VX-702 appears to be most effective against MAPK14, followed by MAPK11 and the remaining members of the family, however exact in vitro IC(50) values have not been published. However a large amount of data is available for in vitro growth inhibition assays where VX-702 exhibits poptent activity, having low IC(50) values beginning at ~16nM and ending at < 400µM for the numerous cell lines tested.

Supplier: AOBChem USA
Description: 1-(3-Bromo-2,4-difluorophenyl)ethanol ≥97%

Catalog Number: (77036-688)
Supplier: Ambeed
Description: 1-(3,4-Difluorophenyl)ethanol 97%


Supplier: AOBChem USA
Description: 1-(3,5-Difluorophenyl)ethanol ≥97% research grade

Supplier: Ambeed
Description: (S)-1-(3,5-Difluorophenyl)ethanol, Purity: 98%, CAS Number: 692732-03-9, Appearance: Liquid, Storage: Sealed in dry, 2-8 C, Size: 1g

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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