You Searched For: 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic+acid


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Supplier: Ambeed
Description: 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid 95%

Catalog Number: (89151-336)
Supplier: Enzo Life Sciences


Catalog Number: (AAJ66364-MD)
Supplier: Thermo Scientific Chemicals
Description: Inhibits the metabolism of folic acid

Supplier: Enzo Life Sciences
Description: Dihydrofolate reductase inhibitor

Supplier: Ambeed
Description: (S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid, Purity: 99% (contain approx 10%water), CAS Number: 59-05-2, Appearance: Form: powder Colour: dark yellow, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 deg C, Size: 10g

Catalog Number: (101914-002)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 058083-100MG , MDL Number: MFCD00075621


Supplier: Ambeed
Description: (4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid hydrate(1:x), Purity: 98%, CAS Number: 133073-73-1, Appearance: Form: Crystal - Powder / Colour: Pale yellow - Yellow - Reddish yellow, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20C, Size: 1G

Supplier: MP Biomedicals
Description: Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds.

SDS

Supplier: BeanTown Chemical
Description: CAS: 59-05-2; EC No: 200-413-8; MDL No: MFCD00150847; RTECS: MA1225000 UN No: UN1544; Haz Class: 6.1; Packing Group: III Powder; Molecular Formula: C20H22N8O5; MW: 454.44 Melting Point: 185-204°

SDS

Supplier: TCI America
Description: CAS Number: 59-05-2
MDL Number: MFCD00150847
Molecular Formula: C20H22N8O5
Molecular Weight: 454.45
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 200
Specific rotation [a]20/D: 21 deg (C=0.1, 1mol/L NaOH sol.)
Supplier: MP Biomedicals
Description: Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Supplier: Ambeed
Description: Sodium (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate, Purity: 98%, CAS Number: 7413-34-5, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 5G

Supplier: Ambeed
Description: 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid 95%

Supplier: Ambeed
Description: Alogliptin benzoate 97%

Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9

New Product

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 058242-1G , MDL Number: MFCD17167308

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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