You Searched For: 4,5-Difluoro-2-methylbenzimidazole


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Supplier: Ambeed
Description: 4,5-Dichloro-2-hydroxybenzaldehyde ≥95%

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Supplier: Ambeed
Description: 3-Bromo-4,5-dimethylnitrobenzene 95%

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Supplier: APOLLO SCIENTIFIC
Description: 3,4-Difluoro-2-methoxybenzaldehyde

Supplier: Matrix Scientific
Description: MF=C9H13No2 MW=167.21 Cas=41864-45-3 MDL=MFCD00130067 5G

Supplier: APOLLO SCIENTIFIC
Description: 3,5-Difluoro-2-hydroxybenzonitrile

Supplier: CUBE BIOTECH
Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-45 - are highly alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-45 gets it's name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.

The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.

Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022

Supplier: AOBChem USA
Description: 3-Bromo-4',5-difluoro-1,1'-biphenyl ≥97%

Supplier: APOLLO SCIENTIFIC
Description: 2,5-Difluoro-4-iodobenzaldehyde

Supplier: Ambeed
Description: α,α-Difluoro-2-(4-methoxyphenyl)acetic acid ≥95%

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Supplier: Ambeed
Description: Lithium difluoro(oxalato)borate 95%

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Supplier: APOLLO SCIENTIFIC
Description: 2,6-Difluoro-m-toluidine 98%

Supplier: APOLLO SCIENTIFIC
Description: 2,6-Difluoro-3-methoxybenzonitrile 98%

Supplier: Ambeed
Description: 2,6-Difluoro-4-hydroxybenzaldehyde 98%

Supplier: Ambeed
Description: 5,7-Difluoro-1-indanone 95%

Supplier: AOBChem USA
Description: 2,3-Difluoro-6-methoxybenzaldehyde ≥95%

Supplier: Ambeed
Description: 2',4'-Difluoro-[1,1'-biphenyl]-4-ol, Purity: 98%, CAS Number: 59089-68-8, Appearance: Off-white solid or liquid, Storage: Inert atmosphere, Room Temperature, Size: 5g

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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