You Searched For: 1-(4-Amino-2-fluorophenyl)-4-methylpiperazine


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Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 045112-5G , MDL Number: MFCD05663793

Supplier: Ambeed
Description: 1-(4-Amino-2-fluorophenyl)-4-methylpiperazine 98%

Supplier: PHARMABLOCK R & D CO MS
Description: 3-fluoro-4-(4-methyl-1-piperazinyl)benzenamine, Purity: 97%, CAS number: 221198-99-8, Molecular Formula: C11H16FN3, Molecular Weight: 209.263, Appearance: Pink solid, Size: 1g

Supplier: Ambeed
Description: N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide, Purity: 98+%, CAS Number: 451492-95-8, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 2mg

Supplier: TCI America
Description: BX-471 ≥98.0% (by HPLC)

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Supplier: Ambeed
Description: (R)-5-((1-Acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide, Purity: 98%, CAS Number: 1448232-80-1, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 1mg

Catalog Number: (77685-071)
Supplier: Ambeed
Description: AV-412 tosylate ≥98%

New Product


Supplier: Ambeed
Description: BX-471 98%

New Product

Supplier: Ambeed
Description: Ensartinib ≥99%

New Product

Supplier: Adipogen
Description: AV-412 is a potent dual inhibitor of EGFR and ErbB2 tyrosine kinases, including the mutant EGFR(L858R,T790M), which is clinically resistant to the EGFR-specific kinase inhibitors erlotinib and gefitinib. In enzyme assays assay the compound inhibited the EGFR variants and ErbB2 in the nanomolar range with over 100-fold selectivity compared with other kinases, apart from ABL and FLT1, which were both moderately sensitive to the compound. In cells, AV-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. It also inhibited epidermal growth factor (EGF)-dependent cell proliferation with an IC(50) of 100nM. Moreover, AV-412 abrogated EGFR signaling in the gefitinib-resistant H1975 cell line, which harbors a double mutation of L858R and T790M in EGFR. In animal studies using cancer xenograft models, AV-412 (30mg/kg) demonstrated complete inhibition of tumor growth of the A431 and BT-474 cell lines, which overexpress EGFR and ErbB2, respectively.

Supplier: AOBChem USA
Description: (3-Bromo-6-chloro-2-fluorophenyl)(4-methylpiperazin-1-yl)methanone ≥97%

Supplier: AOBChem USA
Description: (4-Bromo-2-fluorophenyl)(4-methylpiperazin-1-yl)methanone ≥97%

Catalog Number: (101934-600)
Supplier: Matrix Scientific
Description: MF=C11H15Fn2 MW=194.25 250Mg


Supplier: AOBChem USA
Description: (2,4-Dibromo-6-fluorophenyl)(4-methylpiperazin-1-yl)methanone ≥97%

Catalog Number: (101935-284)
Supplier: Matrix Scientific
Description: MF=C12H15Fn2O2 MW=238.26 250Mg


Supplier: AOBChem USA
Description: (3-Bromo-5-fluorophenyl)(4-methylpiperazin-1-yl)methanone ≥97%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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