You Searched For: 1-(2-Fluoro-5-iodophenyl)ethanol


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Supplier: AOBChem USA
Description: 1-(2-Fluoro-5-iodophenyl)ethanol ≥95%

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Supplier: AOBChem USA
Description: 1-(3-Chloro-2-fluoro-4-iodophenyl)ethanol ≥95%

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Supplier: Ambeed
Description: (S)-1-(5-Fluoro-2-iodophenyl)ethanol, Purity: 97%, CAS Number: 1454847-96-1, Appearance: Solid or liquid, Storage: Keep in dark place, Sealed in dry, 2-8C, Size: 10G

Supplier: Adipogen
Description: AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with an IC(50) of 7nM.

Supplier: Adipogen
Description: GSK1120212 (JTP-74057, trametinib) is a highly specific and potent MEK1 and MEK2 inhibitor with IC(50) values of 0.92nM and 1.8nM respectively.

Supplier: Adipogen
Description: AS703026 is a novel, selective, non-competitive, orally bioavailable MEK1/2 inhibitor with experimental IC(50) values of 5-11nM. In use on multiple myeloma cells (MM), AS703026 inhibited growth and survival of MM cells and cytokine-induced osteoclast differentiation more potently (~10X) than AZD6244. Inhibition of proliferation induced by AS703026 was mediated by G0-G1 cell cycle arrest and was accompanied by reduction of MAF oncogene expression. AS703026 further induced apoptosis via caspase 3 and Poly ADP ribose polymerase (PARP) cleavage in MM cells, both in the presence or absence of bone marrow stromal cells (BMSCs). Importantly, AS703026 sensitized MM cells to a broad spectrum of conventional (dexamethasone, melphalan), novel or emerging (lenalidomide, perifosine, bortezomib, rapamycin) anti-MM therapies. Significant tumour growth reduction in AS703026- vs. vehicle-treated mice bearing H929 MM xenograft tumours correlated with downregulated pERK1/2, induced PARP cleavage, and decreased microvessels in vivo. Moreover, AS703026 (<lt/>200nM) was cytotoxic against the majority of tumour cells tested from patients with relapsed and refractory MM (84%), regardless of mutational status of RAS and BRAF genes. Importantly, BMSC-induced viability of MM patient cells was similarly blocked within the same dose range.

Supplier: Ambeed
Description: 2-(4-Iodophenyl)ethanol 98%

Supplier: AOBChem USA
Description: 1-(2,4-Difluoro-3-iodophenyl)ethanol ≥97%

Supplier: AOBChem USA
Description: 1-(2,3-Difluoro-4-iodophenyl)ethanol ≥97%

Supplier: AOBChem USA
Description: 1-(2,6-Difluoro-4-iodophenyl)ethanol ≥95%

New Product

Supplier: AOBChem USA
Description: 1-(2,6-Difluoro-3-iodophenyl)ethanol ≥95%

New Product

Supplier: AOBChem USA
Description: 1-(2-Bromo-5-iodophenyl)ethanol ≥97%

Supplier: Matrix Scientific
Description: MF=C8H9IO MW=248.06 CAS=52914-23-5 MDL=MFCD00173705 1G

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 048053-5G , MDL Number: MFCD09761464

Supplier: AOBChem USA
Description: (4-Fluoro-3-iodophenyl)methanol ≥97%

Supplier: AOBChem USA
Description: 1-(3-Fluoro-5-iodophenyl)pyrolidine ≥97%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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