You Searched For: NVP-BGJ398


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Catalog Number: (TS468101000)
Supplier: Thermo Scientific Chemicals
Description: Chemical probes can be used to help establish the relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.

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Supplier: Adipogen
Description: NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively.

Supplier: Enzo Life Sciences
Description: Infigratinib is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities.

Supplier: Ambeed
Description: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea, Purity: 99+%, CAS Number: 872511-34-7, Appearance: White to off-white to pale-yellow powder or crystals, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 5mg

Supplier: Ambeed
Description: NVP-AEW541 ≥99%

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Supplier: Ambeed
Description: NVP-AUY922 98%

Supplier: Adipogen
Description: NVP-BSK805 is a potent and selective quinoxaline JAK2 inhibitor with IC(50) values of 0.48, 0.56 and 0.58nM for JAK2 JH1, FL JAK (V617F) and FL JAK2 wt, respectively.

Supplier: Ambeed
Description: NVP-BEP800 ≥98%

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Supplier: Ambeed
Description: 4-(2,6-Difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine, Purity: 98+%, CAS Number: 1092499-93-8, Appearance: Light yellow to yellow powder or crystals, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 2mg

Supplier: Ambeed
Description: TAE684 ≥98%

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Supplier: Ambeed
Description: 4-Methyl-3-((1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)-N-(3-(trifluoromethyl)phenyl)benzamide, Purity: 98%, CAS Number: 940310-85-0, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 deg C, Size: 25mg

Supplier: Ambeed
Description: N-(2-Benzamidobenzo[d]thiazol-6-yl)adamantane-1-carboxamide, Purity: 98+%, CAS Number: 362003-83-6, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5mg

Supplier: Adipogen
Description: NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM.

Supplier: Adipogen
Description: NVP-BEZ235 is an imidazo[4,5-c]quinoline derivative that inhibits PI3K and mTOR kinase activity by binding to the ATP-binding cleft of these enzymes. In cellular settings using human tumor cell lines, this molecule is able to effectively and specifically block the dysfunctional activation of the PI3K pathway, inducing G1 arrest at IC(50) values 3-10nM in biological cell growth and viability assays. In addition NVP-BEZ235 shows effective IC(50) values in in vitro tests against mTor and PI3K family members of 10nM.

Supplier: Ambeed
Description: LXS-196 ≥99%

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Supplier: Ambeed
Description: BEZ235 98+%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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