You Searched For: Tamoxifen+citrate

Catalog Number: (76194-928)

Supplier: Prosci

Description: Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. It is found in two forms, alpha and beta. Both forms are widely expressed, however, alpha is the predominant form in endometrium and breast cancer cells, and beta is more highly expressed in brain, kidney, heart, lung and bone. Activated Estrogen receptor dimerizes and forms both homo- and heterodimers. ER contains five domains: A-F. The A and B domain are able to weakly activate ER in the absence of ligand. The C domain binds DNA and the E domain contains the ligand binding site. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This antibody is specific to estrogen receptor alpha and shows minimal cross-reaction with other members of the family.

Supplier: Biotium

Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Catalog Number: (89360-378)

Supplier: Genetex

Description: HEF1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation. The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation. These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases; two active targets for drug development. HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi. HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells. Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance. This highlights the importance of studying the role of this family of proteins in cancer prognosis.

Supplier: Spectrum Chemicals

Description: Triammonium Citrate, purity: 98 %, CAS number: 3458-72-8, Molecular Formula: C6H17N3O7, Molecular weight: 243.22, Form: Solid, synonyms: Ammonium Citrate Tribasic ; 1,2, 3-Propanetricarboxylic Acid, 2-Hydroxy- Triammonium Salt, size: 500 g

SDS Certificates

Supplier: Thermo Scientific Chemicals

Description: Trimethyl citrate

Supplier: Ambeed

Description: Triethyl citrate 99+%

New Product

Supplier: Thermo Scientific Chemicals

Description: Caffeine citrate

New Product

Supplier: CHEM-IMPEX INTERNATIONAL, INC

Description: Iron(III) citrate

New Product

Supplier: Thermo Scientific Chemicals

Description: Sodium dihydrogen citrate, anhydrous 99%, pure

Supplier: Thermo Scientific Chemicals

Description: Citric acid monosodium salt Sodium dihydrogen citrate. Grade:99, Melting Point C211-212*. Boiling Point C:NA. C6H7NaO7. 18996-35-5.

SDS Certificates

Supplier: TCI America

Description: Sildenafil citrate ≥98.0% (by HPLC)

New Product

Supplier: Spectrum Chemicals

Description: Ferric Citrate, Purified is a powder with a green to reddish-brown appearance. It can also be used in water purification, printing and an acidity regulator.

Supplier: Ambeed

Description: Trisodium citrate ≥98%

New Product

Supplier: Spectrum Chemicals

Description: Ferric Ammonium Citrate, Green, Powder, FCC is also known as Ferric ammonium citrate or Ammonium Iron(III) Citrate and is used as an acidity regulator. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: Ambeed

Description: Magnesium citrate ≥98% (contains 20-32% H₂O)

New Product

Supplier: Spectrum Chemicals

Description: Sodium Citrate, Anhydrous, Powder, FCC is used as a flavorant and preservative. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.