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Catalog Number: (76173-198)
Supplier: Boster Biological Technology
Description: Polyclonal antibody for Sirtuin 2/SIRT2 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Sirtuin 2/SIRT2 information: Molecular Weight: 43182 MW; Subcellular Localization: Nucleus. Cytoplasm, perinuclear region. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Perikaryon . Cell projection . Cell projection, growth cone . Myelin membrane . Deacetylates FOXO3 in the cytoplasm. Colocalizes with PLP1 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. Colocalizes with CDK5R1 in the perikaryon, neurites and growth cone of hippocampal neurons. Colocalizes with alpha-tubulin in neuronal growth cone. Localizes in the cytoplasm and nucleus of germinal vesicle (GV) stage oocytes. Colocalizes with alpha- tubulin on the meiotic spindle as the oocytes enter into metaphase, and also during meiotic anaphase and telophase, especially with the midbody. Colocalizes with PARD3 in internodal region of axons. Colocalizes with acetylated alpha-tubulin in cell projection processes during primary oligodendrocyte precursor (OLP) differentiation (By similarity). Localizes in the cytoplasm during most of the cell cycle except in the G2/M transition and during mitosis, where it is localized in association with chromatin and induces deacetylation of histone at 'Lys-16' (H4K16ac). Colocalizes with SETD8 at mitotic foci. Colocalizes with CDK1 at centrosome during prophase and splindle fibers during metaphase. Colocalizes with Aurora kinase AURKA at centrosome during early prophase and in the centrioles and growing mitotic spindle throughout metaphase. Colocalizes with Aurora kinase AURKB during cytokinesis with the midbody. Colocalizes with microtubules. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins. Shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Colocalizes with EP300 in the nucleus. Translocates to the nucleus and chromatin upon bacterium Listeria monocytogenes infection in interphase cells; Tissue Specificity: Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.


Supplier: VWR International
Description: Create your own flowmeter systems for complete flexibility.

Supplier: VWR International
Description: Type III (soda-lime) glass jars are for collection of soil, sediment, and slurry matrices.
Supplier: VWR International
Description: Create your own flowmeter systems for complete flexibility.

Supplier: Ambeed
Description: 5,8-Dibromoisoquinoline 98%

Supplier: Ambeed
Description: 5,8-Dibromoquinoline 98%

Catalog Number: (77890-418)
Supplier: Ambeed
Description: 5,8-Quinolinequinone 98%

New Product


Supplier: AOBChem USA
Description: 5,8-Dibromoisoquinoline ≥97%

Catalog Number: (89126-604)
Supplier: VWR International
Description: These TraceClean® glass jars are used primarily for the collection of liquid media, soil, sediments, and slurry media for testing semi-volatiles (light sensitive compounds), pesticides, PCBs, diesel range organics, TPH, Metals, and phenolics.

Supplier: Ambeed
Description: 5,8-Dibromoquinoxaline 98%

Supplier: VWR International
Description: These TraceClean® glass jars are used primarily for the collection of soil, sediments, and slurry media for testing Semi-volatiles, Pesticides, PCBs, Diesel Range Organics, TPH, Metals, and Phenolics.
Supplier: Ambeed
Description: DASA-58 98%

New Product

Supplier: MilliporeSigma
Supplier: Ambeed
Description: 2-Chloro-5,8-dimethylquinoline-3-carboxaldehyde 97+%

Supplier: Ambeed
Description: 5,8-Dioxaspiro[3.4]octane-2-methanol ≥97%

New Product

Catalog Number: (77401-694)
Supplier: APOLLO SCIENTIFIC
Description: 5,8-Dihydroxy-1,4-naphthoquinone tech


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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