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Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044212 Beilstein Registry No.: 1908842
Supplier: Adipogen
Description: Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.

Supplier: Adipogen
Description: Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer's disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Autophagy activator.

Supplier: Adipogen
Description: Building block for synthesis.

Catalog Number: (102988-580)
Supplier: Adipogen
Description: Specific histone acetyltransferase Gcn5 inhibitor. Anticancer compound. Pre-mRNA splicing inhibitor. Blocks splicing before the first catalytic steps. Potential anti-inflammatory compound.


Supplier: Adipogen
Description: Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.

Supplier: Adipogen
Description: Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor.

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Supplier: Adipogen
Description: Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.

Supplier: Enzo Life Sciences
Description: Nitrone spin trap for the specific <i>in vivo</i> or <i>in vitro</i> detection of short-lived superoxide, hydroxyl and thiyl radicals.

Supplier: RPI
Description: RPI MUP [4-Methylumbelliferyl Phosphate], CAS: 132-92-3, MW: 402.4, Chemical Formula: C17H19N2O6SNa. H2O, Solubility: Water, Storage Temperature: 2-8 deg C, Appearance: Off white crystalline powder, Purity (1H-NMR spectrum): 98.0 %, Size: 250mg

Supplier: Enzo Life Sciences
Description: p300 HAT activator.

Catalog Number: (AA42289-03)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00062744 Beilstein Registry No.: 1730763

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00000827
Catalog Number: (102609-290)
Supplier: Chem Impex International


Supplier: Enzo Life Sciences
Description: gamma-Secretase inhibitor

Catalog Number: (80601-900)
Supplier: MilliporeSigma
Description: A water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM; micelle MW ~ 23,100; aggregation number ~ 8.1; partial specific volume ~ 0.77 cm3/g). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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