IHR-1 ≥98%

Supplier: ADIPOGEN CORP MS

Synonyms: Inhibitor of Hedgehog Response 1, N,N'-(1,4-Phenylene)bis(2,5-dichlorobenzamide)

AG-CR1-3526-M001 AG-CR1-3526-M005
102988-594EA 48.46 USD
102988-594 102988-596
IHR-1 ≥98%
IHR-1

Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane impermeable Smoothened (Smo) antagonist. Acts on extracellularly exposed Smo only. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.

Formula: C₂₀H₁₂Cl₄N₂O₂
Storage Temperature: Freezer
MDL Number: MFCD03404776
CAS Number: 548779-60-8

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Specification Test Results

Purity 98% (NMR)
Appearance/Color White to grey solid.
Solubility Soluble in DMSO.


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