IHR-1 ≥98%
Supplier: ADIPOGEN CORP MS
Synonyms:
Inhibitor of Hedgehog Response 1, N,N'-(1,4-Phenylene)bis(2,5-dichlorobenzamide)
AG-CR1-3526-M001
AG-CR1-3526-M005
102988-594EA
48.46
USD
102988-594
102988-596
IHR-1 ≥98%
IHR-1
Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane impermeable Smoothened (Smo) antagonist. Acts on extracellularly exposed Smo only. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.
Formula:
C₂₀H₁₂Cl₄N₂O₂ Storage Temperature: Freezer |
MDL Number:
MFCD03404776 CAS Number: 548779-60-8 |
Specification Test Results
Purity |
|
Appearance/Color | White to grey solid. |
Solubility | Soluble in DMSO. |
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