Leucettine L41 ≥98% (by NMR)

Supplier: ADIPOGEN CORP MS

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Synonyms: (5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one

AG-MR-C0023-M001 AG-MR-C0023-M005 AG-MR-C0023-M025

102988-852EA 90 USD

102988-852 102988-854 102988-856

Leucettine L41 ≥98% (by NMR)

Leucettine L41

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer's disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Autophagy activator.

Formula: C₁₇H₁₃N₃O₃
MW: 307.3 g/mol
Storage Temperature: Freezer

CAS Number: 1112978-84-3

Specification Test Results

Purity	98% (NMR)
Appearance/Color	Beige solid.
Solubility	Soluble in DMSO or ethanol.

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