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Supplier: Ambeed
Description: GDC-0449 98%

New Product

Supplier: Enzo Life Sciences
Description: Vismodegib is a potent, novel and specific inhibitor of hedgehog with IC50 of 3 nM and also inhibitor of P-gp with IC50 of 3.0 μM.

Catalog Number: (103444-212)
Supplier: Affymetrix, Inc.
Description: Despite its predicted molecular weight, BANF1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is mouse kidney tissue lysate. PA5-20329 can be used with blocking peptide PEP-0449. Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BAF also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BAF will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BAF is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.

Blocked

Catalog Number: (103334-618)
Supplier: Novus Biologicals
Description: The GDC Antibody (1H7) from Novus Biologicals is a mouse monoclonal antibody to GDC. This antibody reacts with human. The GDC Antibody (1H7) has been validated for the following applications: Western Blot, ELISA.


Supplier: Adipogen
Description: GDC-0032 is a potent, next-generation beta isoform-sparing PI3K inhibitor targeting PI3Kalpha/delta/gamma with Ki of 0.29nM/0.12nM/0.97nM, <gt/>10 fold selective over PI3Kbeta.

Supplier: Ambeed
Description: GDC-0349 ≥98%

New Product

Supplier: Enzo Life Sciences
Description: Cell-permeable, potent inhibitor of PI3 kinase IA and IB

Catalog Number: (AAJ67082-LB0)
Supplier: Thermo Scientific Chemicals
Description: GDC-0068, 98%

Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: ABT-199 (GDC-0199) is a BH3 mimetic that Bcl-2-selective inhibitor with Ki of <0.01 nM. B-cell lymphoma/leukemia 2 (Bcl-2) is an anti-apoptotic protein that controls cell survival by binding the BH3 domains of pro-death BAD and BAK proteins and preventing permeabilization of the mitochondrial outer membrane. This protein is tightly regulated for the homeostasis between cell growth and cell death.A Bcl-2-selective inhibitor with Ki of <0.01 nM

New Product

Supplier: Adipogen
Description: GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).

Supplier: Ambeed
Description: GDC-0623 99+%

Supplier: Adipogen
Description: GDC046 is a potent selective TYK2 inhibitor (Ki=4.8nm) versus JAK1 (Ki=84nm) and JAK2 (Ki=28nm). It is a lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile.

Supplier: Ambeed
Description: 2-(4-(2-(1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide, Purity: 98+%, CAS Number: 1282512-48-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 deg C, Size: 5mg

Supplier: Ambeed
Description: GDC-0941 98+%

Catalog Number: (102192-864)
Supplier: Novus Biologicals
Description: The GDC Antibody from Novus Biologicals is a rabbit polyclonal antibody to GDC. This antibody reacts with human. The GDC Antibody has been validated for the following applications: Western Blot.


Catalog Number: (102192-862)
Supplier: Novus Biologicals
Description: The GDC Antibody from Novus Biologicals is a rabbit polyclonal antibody to GDC. This antibody reacts with human. The GDC Antibody has been validated for the following applications: Western Blot.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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