ABT-199 ≥99%, Moligand™
Supplier: ALADDIN SCIENTIFIC
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Danger
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Synonyms:
GDC-0199, Venetoclax, 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulphonyl)benzamide
ABT-199 (GDC-0199) is a BH3 mimetic that Bcl-2-selective inhibitor with Ki of <0.01 nM. B-cell lymphoma/leukemia 2 (Bcl-2) is an anti-apoptotic protein that controls cell survival by binding the BH3 domains of pro-death BAD and BAK proteins and preventing permeabilization of the mitochondrial outer membrane. This protein is tightly regulated for the homeostasis between cell growth and cell death.A Bcl-2-selective inhibitor with Ki of <0.01 nM
Formula:
C₄₅H₅₀ClN₇O₇S MW: 868.44 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD23160052 CAS Number: 1257044-40-8 |
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