You Searched For: GDC-0349


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Supplier: Ambeed
Description: GDC-0349 ≥98%

New Product

Catalog Number: (103443-996)
Supplier: Affymetrix, Inc.
Description: A suggested positive control is MDA-MB-361 cell lysate. PA5-20216 can be used with blocking peptide PEP-0349. Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR. ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes. ATF6 has two isoforms (ATF6-a and ATF6-b); only ATF6-a is recognized by this antibody.

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Supplier: Chemglass
Description: Oil is specially formulated for use in either belt driven or direct drive vacuum pumps (AF-0349 or AF-0350)

Small Business Enterprise

Supplier: Adipogen
Description: GDC-0032 is a potent, next-generation beta isoform-sparing PI3K inhibitor targeting PI3Kalpha/delta/gamma with Ki of 0.29nM/0.12nM/0.97nM, <gt/>10 fold selective over PI3Kbeta.

Catalog Number: (103334-618)
Supplier: Novus Biologicals
Description: The GDC Antibody (1H7) from Novus Biologicals is a mouse monoclonal antibody to GDC. This antibody reacts with human. The GDC Antibody (1H7) has been validated for the following applications: Western Blot, ELISA.


Supplier: Enzo Life Sciences
Description: Cell-permeable, potent inhibitor of PI3 kinase IA and IB

Supplier: Ambeed
Description: GDC-0623 99+%

Catalog Number: (AAJ67082-LB0)
Supplier: Thermo Scientific Chemicals
Description: GDC-0068, 98%

Supplier: Ambeed
Description: GDC-0941 98+%

Supplier: Ambeed
Description: GDC-0449 98%

New Product

Supplier: Adipogen
Description: GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold).

Supplier: Adipogen
Description: GDC046 is a potent selective TYK2 inhibitor (Ki=4.8nm) versus JAK1 (Ki=84nm) and JAK2 (Ki=28nm). It is a lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile.

Supplier: Ambeed
Description: 2-(4-(2-(1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide, Purity: 98+%, CAS Number: 1282512-48-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 deg C, Size: 5mg

Supplier: Ambeed
Description: (S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamide, Purity: 98+%, CAS Number: 873652-48-3, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 1mg

Supplier: Ambeed
Description: (S)-2-(4-Chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one, Purity: 98%, CAS Number: 1001264-89-6, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Store in freezer, under -20 C, Size: 10mg

Catalog Number: (102192-864)
Supplier: Novus Biologicals
Description: The GDC Antibody from Novus Biologicals is a rabbit polyclonal antibody to GDC. This antibody reacts with human. The GDC Antibody has been validated for the following applications: Western Blot.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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