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Supplier: Cayman Chemical Company
Description: Cyclic di-AMP (sodium salt), Purity: >/=98%, A second messenger produced by bacteria, but not by mammals, Synonyms: c-di-AMP, Cyclic di-Adenosine monophosphate, 3',5'-Cyclic diadenylic acid, Cyclic diadenylate, Size: 5mg

Catalog Number: (89151-482)
Supplier: Enzo Life Sciences
Description: PKA activator.


Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: Adenosine 3′,5′-cyclic monophosphate sodium salt is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is an activator of Epac.Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.

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Supplier: Ambeed
Description: Adenosine-3',5'-cyclic monophosphate sodium salt 95%

Supplier: Thermo Scientific Chemicals
Description: Crystalline powder
Catalog Number: (TCA2112-100MG)
Supplier: TCI America
Description: CAS Number: 37839-81-9
MDL Number: MFCD00069736
Molecular Formula: C10H12N5O6P
Molecular Weight: 351.19
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

Supplier: MilliporeSigma
Description: A key regulator of many cellular reactions.
Supplier: Cayman Chemical Company
Description: 3 3-cGAMP (sodium salt), Purity: >/=98%, Appearance: Crystalline solid, Second messenger, Synonyms: 3',3'-Cyclic GMP-AMP, Adenosine-Guanosine 3',3'-cyclic monophosphate, Adenylyl-(3'?5')-3'-guanylic acid, cyclic nucleotide, disodium salt, c-GpAp, Size: 500ug

Catalog Number: (89151-574)
Supplier: Enzo Life Sciences
Description: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).


Supplier: Cayman Chemical Company
Description: 2 3 cGAMP (sodium salt), Purity: >/=98%, Appearance: solid, A second messenger and inducer of IFN-B production, Synonyms: Adenylyl-(3'?5')-2'-guanylic acid, cyclic nucleotide, disodium salt, Guanosine-Adenosine 2',3'-cyclic monophosphate, Size: 500ug

Catalog Number: (TCD4228-25MG)
Supplier: TCI America
Description: N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Sodium Salt, Purity: >97.0%(HPLC), Cas no: 16980-89-5, MF: C18H23N5NaO8P, MW: 491.37, Synonyms: Bucladesine Sodium Salt, Dibutyryl cAMP Sodium Salt, Size: 25MG


Supplier: Enzo Life Sciences
Description: PKA activator.

Supplier: Ambeed
Description: Dibutyryl-cAMP sodium salt 98%

Supplier: Cayman Chemical Company
Description: ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.

Supplier: Cayman Chemical Company
Description: Cyclic di-GMP (sodium salt), Purity: >/=95%, Cas number: 2222132-40-1, Molecular Formula: C20H22N10O14P2.2Na, Molecular Weight: 734.4 g/mol, Appearance: A solid, Synonyms: 3',5'-Cyclic diguanylic acid, Guanylyl-(3'?5')-3'-guanylic acid, Size: 1mg

Supplier: Cayman Chemical Company
Description: Cyclic di-IMP (sodium salt), Purity: >/=95%, A synthetic second messenger; has mucosal adjuvant properties in vitro and in vivo by the mucosal route, Synonyms: Cyclic di-inosine monophosphate, c-di-IMP, Appearance: A crystalline solid, Size: 500ug

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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