2'3'-cGAMP (sodium salt) ≥98%
Supplier: Cayman Chemical Company
Synonyms:
Guanosine-Adenosine 2',3'-cyclic monophosphate, Adenylyl-(3'→5')-2'-guanylic acid, cyclic nucleotide, disodium salt, 2'-3'-Cyclic GMP-AMP
19887-500
19887-1
76293-140EA
317.21
USD
76293-140
76293-142
2'3'-cGAMP (sodium salt) ≥98%
2'3'-cGAMP (sodium salt)
- A second messenger and inducer of IFN-β production
A second messenger produced from ATP and GTP by cGMP-AMP synthase (cGAS) in the cytoplasm of mammalian cells in response to the presence of DNA; contains a non-canonical 2’5’-phosphodiester bond; binds tightly to the adapter protein STING (Kd = 3.79 nM) and induces IFN-β mRNA expression (EC50 = 19.4 nM in L929 cells)
Specification Test Results
Formulation | A solid |
Purity | ≥98% |
Stability | ≥ 2 years |
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