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Supplier: Thermo Scientific Chemicals
Description: 99% 5G
Supplier: Strem Chemicals Inc
Description: CAS #: 7307-04-2. Size: 25g.

Supplier: Ambeed
Description: 5,5-Dimethylhydantoin 97%

Supplier: CUBE BIOTECH
Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-55 - are highly-alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-55 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general, lighter AASTYs, like 6-55 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.

The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.

Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022

Supplier: Thermo Scientific Chemicals
Description: Fieser: 7,126
Supplier: Thermo Scientific Chemicals
Description: 99% 100G
Catalog Number: (76811-734)
Supplier: Ambeed
Description: 5,5-Diphenylhydantoin, Purity: 99+%, CAS Number: 57-41-0, Appearance: White powder, Storage: Inert atmosphere, Store in freezer, under -20C, Size: 1G


Supplier: TCI America
Description: 2-Bromodibenzothiophene 5,5-Dioxide, Purity: >95.0%(GC), CAS Number: 53846-85-8, Molecular Formula: C12H7BrO2S, Molecular Weight: 295.15, Synonyms: 2-Bromodibenzosulfolane, 2-Bromodibenzothiophene Sulfone, Size: 1G

Catalog Number: (77892-288)
Supplier: Ambeed
Description: 5,5-Difluoropiperidin-2-one ≥97%

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Supplier: MilliporeSigma
Description: Cas Number 57-41-0 5G

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Supplier: TCI America
Description: 3-Bromodibenzothiophene 5,5-Dioxide, Purity: >98.0%(GC), CAS Number: 116668-69-0, Molecular Formula: C12H7BrO2S, Molecular Weight: 295.15, Synonyms: 3-Bromodibenzosulfolane, 3-Bromodibenzothiophene Sulfone, Size: 1G

Supplier: Ambeed
Description: 5,5'-Methylenediisophthalic acid 98%

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Supplier: Ambeed
Description: 5,5-Dimethylpyrrolidin-2-one 98%

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Supplier: Ambeed
Description: 5,5-Dimethyloxazolidin-2-one 95%

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Supplier: Ambeed
Description: Dibenzothiophene-5,5-dioxide 98%

Supplier: BeanTown Chemical
Description: CAS: 77-71-4; EC No: 201-051-3; MDL No: MFCD00005266; RTECS: MU0977000 Crystalline/Powder; Molecular Formula: C5H8N2O2; MW: 128.13 Melting Point: 174-177°

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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