You Searched For: alpha-GalNAc-PEG3-Azide


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Catalog Number: (76084-476)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 and NUMB), an antiapoptotic protein (BAG1), a microtubule motor protein (KIF22), a protein involved in synaptic vesicle function in neurons (SYP), a structural protein (CTNNB1) and SNCAIP. Confers constitutive instability to HIPK2 through proteasomal degradation. It is thereby involved in many cellular processes such as apoptosis, tumor suppression, cell cycle, axon guidance, transcription regulation, spermatogenesis and TNF-alpha signaling. Has some overlapping function with SIAH2. Induces apoptosis in cooperation with PEG3. Upon nitric oxid (NO) generation that follows apoptotic stimulation, interacts with S-nitrosylated GAPDH, mediating the translocation of GAPDH to the nucleus. GAPDH acts as a stabilizer of SIAH1, facilitating the degradation of nuclear proteins.


Supplier: AFG Bioscience
Description: α-D-Mannopyranosyl azide 95%

Supplier: AFG Bioscience
Description: 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azide 97%

Supplier: AFG Bioscience
Description: Fmoc-L-Ser (β-D-GalNAc(Ac)3)-OH ≥95%

Supplier: AFG Bioscience
Description: Fmoc-L-Thr (Gal β(1-3)GalNAc)-OH, peracetate ≥95%

Supplier: Ambeed
Description: Tri-GalNAc(OAc)3 TFA 98%

New Product

Supplier: TCI America
Description: Poly(2-methyl-2-oxazoline) Azide Terminated n=∼50, ULTROXA®

New Product

Catalog Number: (TCG0344-5MG)
Supplier: TCI America
Description: CAS Number: 59837-15-9
Molecular Formula: C20H28N2O13
Molecular Weight: 504.45
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Storage Temperature: <0°C

SDS


Supplier: TCI America
Description: Poly(2-ethyl-2-oxazoline) Azide Terminated n=∼50, ULTROXA®

New Product

Catalog Number: (102134-324)
Supplier: Novus Biologicals
Description: The TNF-alpha Antibody - Azide Free from Novus Biologicals is a rabbit polyclonal antibody to TNF-alpha. This antibody reacts with human, mouse, rat, primate. The TNF-alpha Antibody - Azide Free has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.


Supplier: AFG Bioscience
Description: β-Gal-PEG3-Amine 95%

Supplier: Ambeed
Description: Amino-PEG3-acid 95%

New Product

Catalog Number: (103289-712)
Supplier: Novus Biologicals
Description: The CD25 / IL-2 R alpha Antibody (280414) - Azide Free from Novus Biologicals is a rat monoclonal antibody to CD25 / IL-2 R alpha. This antibody reacts with mouse. The CD25 / IL-2 R alpha Antibody (280414) - Azide Free has been validated for the following applications: Flow Cytometry.


Catalog Number: (102205-230)
Supplier: Novus Biologicals
Description: The Polypeptide GalNac Transferase 3 / GALNT3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Polypeptide GalNac Transferase 3 / GALNT3. This antibody reacts with rat. The Polypeptide GalNac Transferase 3 / GALNT3 Antibody has been validated for the following applications: Western Blot.


Supplier: AFG Bioscience
Description: β-GlcNAc-PEG3-Amine 95%

Supplier: AFG Bioscience
Description: β-Glc-PEG3-Alkyne 95%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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