You Searched For: Smoothened+agonist+dihydrochloride+hydrate


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Supplier: Adipogen
Description: Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

Catalog Number: (AAJ65248-MCR)
Supplier: Thermo Scientific Chemicals
Description: Oil

Supplier: Adipogen
Description: Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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Catalog Number: (89147-870)
Supplier: Enzo Life Sciences
Description: Smoothened ligand

SDS


Catalog Number: (102988-564)
Supplier: Adipogen
Description: Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.


Catalog Number: (102988-566)
Supplier: Adipogen
Description: Cell permeable highly active Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist.


Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: AMN082 dihydrochloride, a selective,  and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors.

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Supplier: Enzo Life Sciences
Description: Inhibits Rho kinase (ROCK; Ki=0.33μM). Selective protein kinase A and G inhibitor (both Ki’s = 1.6μM). Inhibits agonist-induced activation of NADPH oxidase in human neutrophils (IC50=15μM). Inhibitor of myosin light chain kinase and Ca2+/calmodulin-dependent protein kinase II. Inhibits translocation of PKCβI, PKCβII and PKCζ. Cell permeable Ca2+ antagonist with antivasospastic properties.

Supplier: Ambeed
Description: Quinacrine dihydrochloride hydrate 98%

Supplier: Thermo Scientific Chemicals
Description: 3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate 98+%

Supplier: Thermo Scientific Chemicals
Description: . Grade:98, Melting Point ca 264*[degree]C. Boiling Point C:NA. C8H11Cl2N3. xH2O. 5993-91-9.
Supplier: Thermo Scientific Chemicals
Description: Excellent colorimetric substrate for detection of horseradish peroxidase labelled probes and is used with peroxidase and peroxidase coupled systems, particularly in ELISA techniques, blue result.
Supplier: Thermo Scientific Chemicals
Description: Puromycin dihydrochloride hydrate 99%

Supplier: Adipogen
Description: Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice.

Supplier: Ambeed
Description: (S)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride hydrate, Purity: 99%, CAS number: 191217-81-9, Appearance: White to light-yellow powder or crystals, Storage: Inert atmosphere, Room Temperature, Size: 5G

Supplier: Ambeed
Description: 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanamine dihydrochloride hydrate, Purity: 95%, CAS Number: 2828446-98-4, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1g

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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