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(R)-CR8 ≥98% (by NMR)

Supplier: Adipogen
Description: Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor. Apoptosis inducer. Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.

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Image Unavailable-AA42284-09

N,N-Dimethylformamide-[D₇] (99.5% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00003286

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Image Unavailable-102515-954

1-Methyl-3,4-bis(3-indolyl)maleimide ≥98% (by NMR)

Supplier: Adipogen
Description: Negative control for protein kinase C (PKC) inhibitors. S6K inhibitor. Necrosis inhibitor.

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Image Unavailable-102988-838

(2'Z,3'E)-6-Bromoindirubin-3'-oxime ≥99% (by NMR)

Supplier: Adipogen
Description: Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Anticancer compound. Potent antiproliferative agent. Suppresses metastasis. Apoptosis inducer. Sustains pluripotency and self-renewal of human and mouse embryonic stem cells (ESCs) by activation of the Wnt signaling pathway. Anti-leishmanial (IC50 = 0.150µM). Proto-oncogene tyrosine-protein kinase receptor RET inhibitor (IC50=0.51µM). Inhibits HIV-1 transcription and protects against Tat induced neurotoxicity.

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Methanol-[D₁] (99.5% D) (Isotopic) for NMR spectroscopy

Catalog Number: (AA89571-14)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044213 Beilstein Registry No.: 1730948

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Image Unavailable-AA42341-KV

Pyridine-[D₅] (99.5% D) (Isotopic) for NMR spectroscopy

Catalog Number: (AA42341-KV)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044639 Beilstein Registry No.: 114377

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Image Unavailable-102515-912

BAY 11-7082 ≥99% (by NMR)

Supplier: Adipogen
Description: IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. NLRP3 inflammasome inhibitor. Reduces ATPase activity of the NLRP3 inflammasome. Inhibits platelet aggregation.

Small Business Enterprise

Image Unavailable-AA42270-KV

Chloroform-[D₁] (100% D) (Isotopic) for NMR spectroscopy

Catalog Number: (AA42270-KV)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00000827 Notes: Minimum isotopic purity 99.96%

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Image Unavailable-102516-082

Cyclic pifithrin-alpha-hydrobromide ≥98% (by NMR)

Supplier: Adipogen
Description: Stable analog of pifithrin-alpha. p53 inhibitor.

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Image Unavailable-102990-684

N-(3-Oxododecanoyl)-L-homoserine lactone ≥98% (by NMR)

Supplier: Adipogen
Description: Quorum sensing agent.

Image Unavailable-102988-916

(+)-Flavipucine (from Phoma sp. BS 7204) ≥96% (by 1H-NMR, HPLC)

Catalog Number: (102988-916)
Supplier: Adipogen
Description: (+)-Flavipucine is an anti-bacterial and anti-fungal compound.
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Phenyl propargyl ether

Supplier: Adipogen
Description: Aromatic terminal alkynes. Building block for synthesis. The terminal alkyne functionality has a wide range of applications.

Image Unavailable-AA42357-09

Trifluoroacetic acid-[D₁] (99.5% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044563

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Image Unavailable-102989-058

Cytochalasin J

Catalog Number: (102989-058)
Supplier: Adipogen
Description: Mycotoxin. Phytotoxic and cytotoxic agent. Immunosuppressive activity. Affects chromosome congression and spindle microtubule organization in PtK1 cells. Actin and myosin inhibitor.
Image Unavailable-102515-880

D-erythro-Dihydrosphingosine 1-phosphate ≥98% (by NMR)

Supplier: Adipogen
Description: Saturated analog of sphingosine 1-phosphate (1-SP1). Ligand for sphingosine 1-phosphate (S1P/EDG) receptors. Negative control for intracellular effects of sphingosine 1-phosphate. Induces chemotaxis. Antifibrotic.

Small Business Enterprise

Image Unavailable-102988-592

7-Azido-4-methylcoumarin ≥98% (by NMR)

Supplier: Adipogen
Description: Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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