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D-erythro-Dihydrosphingosine 1-phosphate ≥98% (by NMR)

Supplier: Adipogen
Description: Saturated analog of sphingosine 1-phosphate (1-SP1). Ligand for sphingosine 1-phosphate (S1P/EDG) receptors. Negative control for intracellular effects of sphingosine 1-phosphate. Induces chemotaxis. Antifibrotic.

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Image Unavailable-102988-592

7-Azido-4-methylcoumarin ≥98% (by NMR)

Supplier: Adipogen
Description: Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency.

Image Unavailable-AA42280-06

1,2-Dichlorobenzene-[D₄] (99% D) (Isotopic) for NMR spectroscopy

Catalog Number: (AA42280-06)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00037106

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Image Unavailable-102991-078

Tris[3,5-bis(trifluoromethyl)phenyl]phosphine

Supplier: Adipogen
Description: A phosphine with enhanced solubility in solvents. Phosphines are used as ligands for many metal complexes.

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n-Octane-[D₁₈] (99% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00037626

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Product Image-76460-012

SP Wilmad-LabGlass, Variable Temperature NMR Spinner Turbine for use with Bruker® Spectrometers, SP Industries

Catalog Number: (76460-012)
Supplier: SP Industries
Description: Manufactured to precision standards that exceed the spectrometer manufacturers requirements.
Image Unavailable-102516-242

BAY 58-2667 hydrochloride ≥98% (by NMR)

Catalog Number: (102516-242)
Supplier: Adipogen
Description: Nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Shows potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity. Anti-aggregating agent.

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1,4-Phenylene diisothiocyanate

Supplier: Adipogen
Description: Reagent for solid-phase sequencing.

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Dimethyl sulfoxide-[D₆] (99.96% D) for NMR spectroscopy

Supplier: Cambridge Isotope Labs Inc
Description: Dimethyl sulfoxide-[D₆] (99.96% D) for NMR spectroscopy

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Papaverine Hydrochloride

Supplier: Adipogen
Description: Smooth muscle relaxant and vasodilator. Phosphodiesterase PDE10A inhibitor. Antiviral. Antipsychotic. Potential inducer of browning in WAT.

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NU6102 ≥98% (by NMR)

Supplier: Adipogen
Description: Potent CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM) inhibitor. 1'000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6 µM), DYRK1A (IC50 = 0.9 µM), PDK1 (IC50 = 0.8 µM) and ROCK-II (IC50 = 0.6 µM). Inhibits cell growth.

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Image Unavailable-TS217350100

Dichloromethane-[D₂] 99.6+ atom % D for NMR spectroscopy

Catalog Number: (TS217350100)
Supplier: Thermo Scientific Chemicals
Description: Packaged in 1.00 ml ampoules

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Image Unavailable-80051-926

Glyco-SNAP-2

Catalog Number: (80051-926)
Supplier: MilliporeSigma
Description: A stable, water-soluble nitric oxide (NO) donor (<sup>1</sup>/<sub>2</sub>=27 hours) with properties similar to those of Glyco-SNAP-1 (80051-924). Dissolve in aqueous buffer immediately after use.
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3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥98% (by NMR)

Supplier: Adipogen
Description: Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).

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Image Unavailable-AA42319-KV

Methanol-[D₄] (99.8% D) (Isotopic) + 0.05% v/v TMS for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044637

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Image Unavailable-H-4902.0001BA

E-76

Catalog Number: (H-4902.0001BA)
Supplier: Bachem Americas
Description: Anticoagulant and antithrombotic peptides. Please see also the product family 'Hirudin Fragments and Analogs', the inhibitors N-1065, N-1215, N-1260, N-1565, and N-1970, and the anticoagulant anisindione, Q-1085.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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