(2'Z,3'E)-6-Bromoindirubin-3'-oxime ≥99% (by NMR)

Supplier: ADIPOGEN CORP MS
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Synonyms: GSK 3 Inhibitor IX, BIO, 6BIO, 6-Bromoindirubin-3'-oxime, (2Z,3E)-6'-Bromo-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one

AG-MR-C0019-M010 AG-MR-C0019-M050
102988-836EA 180 USD
102988-836 102988-838
(2'Z,3'E)-6-Bromoindirubin-3'-oxime ≥99% (by NMR)
(2'Z,3'E)-6-Bromoindirubin-3'-oxime

Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Anticancer compound. Potent antiproliferative agent. Suppresses metastasis. Apoptosis inducer. Sustains pluripotency and self-renewal of human and mouse embryonic stem cells (ESCs) by activation of the Wnt signaling pathway. Anti-leishmanial (IC50 = 0.150µM). Proto-oncogene tyrosine-protein kinase receptor RET inhibitor (IC50=0.51µM). Inhibits HIV-1 transcription and protects against Tat induced neurotoxicity.

Formula: C₁₆H₁₀BrN₃O₂
MW: 356.18 g/mol
Storage Temperature: Freezer
MDL Number: MFCD08705318
CAS Number: 667463-62-9

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Specification Test Results

Purity 99% (NMR)
Appearance/Color Dark red solid.
Solubility Soluble in DMSO or ethanol.

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