7-Azido-4-methylcoumarin ≥98% (by NMR)

Supplier: ADIPOGEN CORP MS
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Synonyms: 7-Azido-4-methyl-1-benzopyran-2-one

AG-CR1-3525-M001 AG-CR1-3525-M005
102988-590EA 48.46 USD
102988-590 102988-592
7-Azido-4-methylcoumarin ≥98% (by NMR)
7-Azido-4-methylcoumarin

Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency.

Formula: C₁₀H₇N₃O₂
MW: 201.2 g/mol
Storage Temperature: Freezer
MDL Number: MFCD16652405
CAS Number: 95633-27-5

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Specification Test Results

Purity >98% (NMR)
Appearance/Color White to yellow solid.
Solubility Soluble in DMSO.

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