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L-α-Aminoadipic acid ≥98% (by NMR), Powder

Catalog Number: (100294-918)

Supplier: Indofine Chemical Company

Description: Rare Organics & BioChemicals 1118-90-7 1gm H-2-Aad-OH 161.2 Room temperature.

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N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride ≥98% (by NMR)

Supplier: Adipogen

Description: Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor.

Cyclohexane-[D₁₂] (99.5% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00044212 Beilstein Registry No.: 1908842

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Aminopurvalanol A ≥97% (by 1H-NMR)

Supplier: Enzo Life Sciences

Description: CDK/cyclin inhibitor

WSP1 ≥97% (by NMR)

Supplier: Adipogen

Description: Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.

DAPT ≥98% (by NMR)

Supplier: Enzo Life Sciences

Description: gamma-Secretase inhibitor

Leucettine L41 ≥98% (by NMR)

Supplier: Adipogen

Description: Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer's disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down syndrome (inhibition of DYRK1A). Neuroprotective against glutamate-induced cell death. Autophagy activator.

2,2-Dimethylcyclopentanone

Supplier: Adipogen

Description: Building block for synthesis.

SAG analog (trans isomer) ≥98% (by NMR), low toxicity

Catalog Number: (102988-564)

Supplier: Adipogen

Description: Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

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N-Decanoyl-L-homoserine lactone ≥98% (by NMR)

Supplier: Adipogen

Description: N-Decanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include regulation of virulence and exoproteases.

MS-1020 ≥95% (by NMR)

Catalog Number: (102516-216)

Supplier: Adipogen

Description: Selective JAK3 inhibitor. Blocks STAT signaling. Inducer of apoptosis via down-regulation of anti-apoptotic gene expression.

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IHR-1 ≥98% (by NMR)

Supplier: Adipogen

Description: Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane impermeable Smoothened (Smo) antagonist. Acts on extracellularly exposed Smo only. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.