You Searched For: Methotrexate+hydrate


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Supplier: TCI America
Description: CAS Number: 59-05-2
MDL Number: MFCD00150847
Molecular Formula: C20H22N8O5
Molecular Weight: 454.45
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 200
Specific rotation [a]20/D: 21 deg (C=0.1, 1mol/L NaOH sol.)
Supplier: Ambeed
Description: Methotrexate hydrate 98%

New Product

Supplier: MP Biomedicals
Description: Folinic acid calcium salt, pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate.
Supplier: MORAVEK BIOCHEMICALS MS
Description: Methotrexate, disodium salt, [3',5',7-3H(N)] ≥97% (by HPLC), MORpure™

Supplier: Ambeed
Description: Methotrexate 99% (contain ~10% water)

New Product

Catalog Number: (AAJ66364-MD)
Supplier: Thermo Scientific Chemicals
Description: Inhibits the metabolism of folic acid

Supplier: Enzo Life Sciences
Description: Dihydrofolate reductase inhibitor

Catalog Number: (89138-112)
Supplier: Biotium
Description: Fluorescein methotrexate is useful for studying anti-metabolite resistance and spontaneous gene amplification. The dye is actively taken up by cells and binds to dihydrofolate reductase (DHFR) quantitatively.


Supplier: BeanTown Chemical
Description: CAS: 59-05-2; EC No: 200-413-8; MDL No: MFCD00150847; RTECS: MA1225000 UN No: UN1544; Haz Class: 6.1; Packing Group: III Powder; Molecular Formula: C20H22N8O5; MW: 454.44 Melting Point: 185-204°

SDS

Supplier: Ambeed
Description: Sodium (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate, Purity: 98%, CAS Number: 7413-34-5, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 5G

Catalog Number: (77694-540)
Supplier: LGC STANDARDS
Description: 7-Hydroxy Methotrexate Ammonium Salt, TRC, LGC Standards

New Product


Supplier: MP Biomedicals
Description: Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Catalog Number: (75786-344)
Supplier: Enzo Life Sciences
Description: Ultra sensitive Methotrexate ELISA kit enabling detection of Methotrexate in serum, plasma, and urine in just 1.5 hours.

SDS


Supplier: MP Biomedicals
Description: Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds.

SDS

Catalog Number: (77694-721)
Supplier: LGC STANDARDS
Description: Methotrexate Disodium Salt, TRC, LGC Standards

New Product


Catalog Number: (76715-456)
Supplier: AFG BIOSCIENCE LLC
Description: Human Methotrexate (MTX) ELISA Kit


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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