You Searched For: Boc-3,5-diiodo-D-tyrosine


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Catalog Number: (77168-190)
Supplier: Ambeed
Description: 2,4-diiodo-5-methoxyaniline, Purity: 95+%, CAS Number: 117832-18-5, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 100mg


Catalog Number: (10260-008)
Supplier: Bioss
Description: Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.


Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 042447-1G , MDL Number: MFCD04974255

Supplier: Matrix Scientific
Description: 4,6-Diiodo-2-methylpyrimidine 95

Catalog Number: (10260-010)
Supplier: Bioss
Description: Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.


Catalog Number: (77158-420)
Supplier: Ambeed
Description: 2,6-Diiodo-4-(trifluoromethyl)phenol, Purity: 95%, CAS Number: 169255-50-9, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 1g


Supplier: Ambeed
Description: (S)-2,2'-diiodo-1,1'-binaphthalene 95+%

New Product

Supplier: AOBChem USA
Description: 2-Fluoro-1,3-diiodo-4-methylbenzene ≥97%

Catalog Number: (TCD5547-200MG)
Supplier: TCI America
Description: 5,6-Difluoro-4,7-diiodo-2,1,3-benzothiadiazole ≥98.0% (by GC)

New Product


Catalog Number: (10393-548)
Supplier: Bioss
Description: MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uterus.


Catalog Number: (101839-272)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 035246-250MG , MDL Number: MFCD11857683


Catalog Number: (101805-000)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 016577-500MG , MDL Number: MFCD06656523


Supplier: TCI America
Description: CAS Number: 3268-21-1
MDL Number: MFCD00142554
Molecular Formula: C10H12I2
Molecular Weight: 386.01
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Melting point (°C): 140

SDS

Catalog Number: (75791-928)
Supplier: Prosci
Description: Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.


Catalog Number: (75791-926)
Supplier: Prosci
Description: Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.


Supplier: Ambeed
Description: (R)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene 98%, Ambeed.Inc

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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