You Searched For: Afatinib


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Supplier: Thermo Scientific Chemicals
Description: Afatinib 96%

Supplier: Adipogen
Description: Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines expressing wild-type EGFR, selected EGFR exon 19 deletion mutations, or exon 21 L858R mutations. It also inhibited in vitro proliferation of cell lines overexpressing HER2. Overall, tumor growth was inhibited by Afatinib very effectively with low nanomolar IC(50) values ranging from approximately 6nM to below 500nM.

Supplier: TCI America
Description: Afatinib ≥97.0% (by HPLC, total nitrogen)

New Product

Supplier: Ambeed
Description: Afatinib 99%

New Product

Supplier: TLC Standards
Description: Pharmaceutical Standards, Afatinib Impurity 12

New Product

Supplier: TLC Standards
Description: Pharmaceutical Standards, Afatinib Impurity C

New Product

Supplier: TLC Standards
Description: Pharmaceutical Standards, Afatinib N-Oxide

New Product

Supplier: Ambeed
Description: (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide dimaleate ≥98%

New Product

Catalog Number: (103960-976)
Supplier: ASTATECH INC MS
Description: AFATINIB 1G

Blocked

Catalog Number: (103960-978)
Supplier: ASTATECH INC MS
Description: AFATINIB 5G

Blocked

Catalog Number: (103781-878)
Supplier: R&D Systems
Description: AFATINIB DIMALEATE INHIBITOR >/=98% 10MG


Catalog Number: (103204-404)
Supplier: ASTATECH INC MS
Description: AFATINIB, FREE BASE 99% 485.94 0.25G

Blocked

Catalog Number: (103960-974)
Supplier: ASTATECH INC MS
Description: AFATINIB 0.25G

Blocked

Catalog Number: (MSPP-A3145)
Supplier: APEXBIO TECH MS
Description: AFATINIB DIMALEATE 10MM IN 1ML DMSO

New Product


Catalog Number: (103963-676)
Supplier: ASTATECH INC MS
Description: AFATINIB IM 1 0.1G

Blocked

Catalog Number: (103208-292)
Supplier: ASTATECH INC MS
Description: AFATINIB, FREE BASE 99% 850140-72-6 1G

Blocked

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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