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Supplier: TCI America
Description: CAS Number: 2487-40-3
MDL Number: MFCD00031505
Molecular Formula: C5H4N4OS
Molecular Weight: 168.17
Purity/Analysis Method: >80.0% (HPLC)
Form: Crystal
Color: Very Pale Yellow
Supplier: MP Biomedicals
Description: Adenine is a purine nucleobase. It is widespread throughout animal and plant tissues combined with niacinamide, D-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coalaninedehydrase.

SDS

Catalog Number: (TCD3600-25G)
Supplier: TCI America
Description: CAS Number: 479-18-5
MDL Number: MFCD00005759
Molecular Formula: C10H14N4O4
Molecular Weight: 254.25
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 163

Supplier: Adipogen
Description: Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.

Supplier: Spectrum Chemicals
Description: Guanine, Reagent, also known as 2-amino-6-hydroxypurine, is one of the four main nucleobases found in the nucleic acids DNA and RNA. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.
Catalog Number: (102987-452)
Supplier: Adipogen
Description: Potent, selective and cell-permeable inhibitor of Nedd8 E1 Activating Enzyme (NAE). By inhibiting the Neddylation pathway this molecule disrupts cullin-RING ligase activity, leading to inhibition of proliferation or apoptotic death of various human tumor cells through the deregulation of S-phase DNA synthesis.


Supplier: Adipogen
Description: Baricitinib is a selective JAK1 and JAK2 inhibitor. IC(50) values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 and IL-23 at concentrations of <lt/> 50nM, and also showed good efficacy in a number of animal models at doses of 10mg/kg and below. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development as a potential treatment for psoriasis and diabetic nephropathy

Supplier: Adipogen
Description: A metabolite of caffeine with antioxidant and neuroprotective activities. Does not inhibit the differentiation of 3T3-L1 pre-adipocytes to mature adipocytes, but suppress the intracellular lipid accumulation after complete differentiation in a dose-dependent manner.

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 054810-500MG , MDL Number: MFCD16140309

Supplier: Adipogen
Description: Purine alkaloid related to caffeine. Potent antioxidant. Not through direct scavenging of ROS but strengthen antioxidant systems in vivo. Anti-inflammatory and antinociceptive compound. Suggested to have adenosine receptor agonistic activity and also acting on dopamine receptors. Shown to have potent sedative and hypnotic properties. Ameliorated learning and memory impairments caused by central fatigue. Shown to inhibit cAMP-specific PDE4 and cGMP-specific PDE5 activity in vivo and in vitro. Increased glucose level, decreased lactic acid concentration, reduced LDH activity and elevated the expressions of both GLUT1/3 in restraint-stressed mice. Can increase the solubility of aromatic systems in water.

Supplier: Adipogen
Description: Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.

Supplier: Spectrum Chemicals
Description: Uric Acid, Reagent is a product of the metabolic breakdown of purine nucleotides. High blood concentrations of uric acid can lead to gout. The chemical is associated with other medical conditions including diabetes and the formation of ammonium acid urate kidney stones. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.

Small Business Enterprise

Supplier: Adipogen
Description: Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.

Supplier: Ambeed
Description: Purine 98%

Catalog Number: (102834-982)
Supplier: Matrix Scientific
Description: 2-Chloro-7H-purin-6-amine ≥97%


Supplier: Ambeed
Description: 2-Chloro-7H-purin-6-amine 97%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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