Baricitinib phosphate salt ≥95%

Supplier: ADIPOGEN CORP MS

Synonyms: LY-3009104, 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulphonyl)azetidin-3-yl)acetonitrile phosphate, Baricitinib phosphate

SYN-1117-M001 SYN-1117-M005 SYN-1117-M010 SYN-1117-M050
102992-154EA 246.46 USD
102992-154 102992-156 102992-158 102992-160
Baricitinib phosphate salt ≥95%
Baricitinib phosphate salt

Baricitinib is a selective JAK1 and JAK2 inhibitor. IC(50) values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 and IL-23 at concentrations of 50nM, and also showed good efficacy in a number of animal models at doses of 10mg/kg and below. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development as a potential treatment for psoriasis and diabetic nephropathy

Formula: C₁₆H₁₇N₇O₂S·H₃PO₄
MW: 469.4 g/mol
Storage Temperature: Freezer
MDL Number: MFCD25976707
CAS Number: 1187595-84-1

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO or ethanol.

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