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Catalog Number: (10284-392)
Supplier: Bioss
Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.


Catalog Number: (10297-240)
Supplier: Bioss
Description: The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.


Catalog Number: (10284-386)
Supplier: Bioss
Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.


Catalog Number: (10284-388)
Supplier: Bioss
Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.


Catalog Number: (10284-384)
Supplier: Bioss
Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.


Supplier: Adipogen
Description: For the labeling of amino acids and their detection in picomolar amounts.

Supplier: Thermo Scientific Chemicals
Description: Pyridoxal hydrochloride 99%
Supplier: Ambeed
Description: 4-Pyridoxic acid 97%

Supplier: Ambeed
Description: Pyridoxal hydrochloride 98%

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Catalog Number: (IC10276705)
Supplier: MP Biomedicals
Description: Pyridoxal hydrochloride is used for labeling amino acids and for their detection in the picomole range.

Catalog Number: (103271-576)
Supplier: Novus Biologicals
Description: The Pyridoxal Kinase / PDXK Antibody from Novus Biologicals is a rabbit polyclonal antibody to Pyridoxal Kinase / PDXK. This antibody reacts with human. The Pyridoxal Kinase / PDXK Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.


Catalog Number: (103271-578)
Supplier: Novus Biologicals
Description: The Pyridoxal Kinase / PDXK Antibody from Novus Biologicals is a rabbit polyclonal antibody to Pyridoxal Kinase / PDXK. This antibody reacts with human, mouse. The Pyridoxal Kinase / PDXK Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.


Catalog Number: (76701-924)
Supplier: AFG Bioscience
Description: Human pyridoxal,pyridoxine vitamin B6-kinase(PDXK) ELISA Kit


Catalog Number: (76714-426)
Supplier: AFG BIOSCIENCE LLC
Description: Human pyridoxal,pyridoxine vitamin B6-phosphatase(PDXP) ELISA Kit


Catalog Number: (103335-210)
Supplier: Novus Biologicals
Description: The Pyridoxal Kinase / PDXK Antibody (4G6) from Novus Biologicals is a mouse monoclonal antibody to Pyridoxal Kinase / PDXK. This antibody reacts with human. The Pyridoxal Kinase / PDXK Antibody (4G6) has been validated for the following applications: Western Blot, ELISA.


Supplier: Ambeed
Description: N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide 98%

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