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(R)-3-Hydroxymyristic acid ≥98% (by NMR)

Supplier: Adipogen
Description: Hydroxy fatty acid used to study its role in biological processes such as oxidative stress, inflammation and insulin resistance. Used in endotoxin and lipid A research, since it is one of two major components of bacterial Lipid A. Shows antifungal activity. Compound could be used as analytical reference in assaying food samples.

Image Unavailable-AA87857-18

Sulfuric acid-[D₂] 96% (99.5% D) (w/w) in D₂O for NMR spectroscopy

Catalog Number: (AA87857-18)
Supplier: Thermo Scientific Chemicals
Description: 96-98% in D2O, 99.5% (Isotopic). 50g.

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Image Unavailable-89139-292

4-Bromo-A-23187 free acid ≥98% (by TLC, NMR) ionophore, for calcium determination

Catalog Number: (89139-292)
Supplier: Biotium
Description: Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2 indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2 to enter cells to quench indicator fluorescence. However, since 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2 indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.
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Nocodazole ≥98% (by NMR)

Supplier: Adipogen
Description: Microtubule inhibitor. Antitumor compound. Mitosis inhibitor. Arrests the cell cycle at G2/M phase. Promotes tubulin depolymerization. Induces fragmentation of the Golgi complex. Inhibits the T cell antigen receptor. Stimulates the intrinsic GTPase activity of tubulin. Activates the JNK/SAPK signaling pathway. Apoptosis inducer. Autophagy inhibition through prevention of autophagosome-lysosome fusion.

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Dimethyl sulfoxide-[D₆] (100% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00002090 Notes: Minimum isotopic purity 99.96%

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Image Unavailable-102515-868

H-89 dihydrochloride ≥98% (by NMR)

Supplier: Adipogen
Description: Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Protein kinase Cµ (PKCµ) inhibitor. Ca2+/calmodulin-dependent protein kinase II inhibitor. Casein kinase I inhibitor. Myosin light chain kinase (MLCK) inhibitor. Apoptosis enhancer. Tool to study protein crystal structure-inhibitor interactions. Rho kinase inhibitor. Cell proliferation inhibitor. Review.

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Image Unavailable-AA42291-03

1,1,1,3,3,3-Hexafluoro-2-propanol-[D₂] (98% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: 98% (Isotopic),UN1760,Liquid, packaged in prescored ampoules,DANGER: CORROSIVE, irritates skin & eyes,5x1g,1g,CORROSIVE,

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Image Unavailable-AA42286-KV

Dimethyl sulfoxide-[D₆] (100% D) (Isotopic) + 0.03% v/v TMS for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00002090 Minimum isotopic purity 99.96%

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Image Unavailable-76002-018

KN-93 phosphate ≥98% (by 1H-NMR)

Supplier: Enzo Life Sciences
Description: CaM kinase II inhibitor

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Alsterpaullone ≥98% (by NMR)

Supplier: Adipogen
Description: Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor.

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Image Unavailable-102516-232

Smoothened Agonist ≥98% (by NMR)

Supplier: Adipogen
Description: Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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Image Unavailable-102516-146

2-Morpholino-8-phenylchromone ≥99% (by NMR)

Supplier: Adipogen
Description: Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

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Product Image-89147-930

4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline ≥97% (by 1H-NMR)

Catalog Number: (89147-930)
Supplier: Enzo Life Sciences
Description: Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=51nM). Displays ~15-fold greater selectivity over p38α MAPK (IC50=740nM). Inhibits TGF-β-dependent cellular growth (IC50=89nM in NIH 3T3 mouse fibroblasts) and transcription activation (IC50=47nM in mink lung cells). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay.
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L-4-Cyanophenylalanine 98% (by NMR)

Supplier: Thermo Scientific Chemicals
Description: 4-Cyano-L-phenylalanine, 98%

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Product Image-PI21580

BS3 (Bis(sulfosuccinimidyl) suberate sodium salt) ≥93% (by NMR), Pierce™

Supplier: Invitrogen
Description: Thermo Scientific Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

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2-Propanol-[D₈] (99% D) (Isotopic) for NMR spectroscopy

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044341

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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