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Supplier: Adipogen
Description: Apoptosis inducer. Cell cycle arrest inducer. Anticancer compound Antioxidant. Hepatoprotective. Inhibits TGF-beta/Smad-mediated fibrogenesis. Stimulates wound healing. Anti-diabetic. Glycogen phosphorylase inhibitor. Neuroprotective. Modulates multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance. Down regulates BACE1 and increases ADAM10 maturation. Anti-hyperglycemic compound. Anti-inflammatory and antinociceptive compound. Antiangiogenic. Acetylcholinesterase (AChE) inhibitor. PPARgamma inhibitor through a C/EBPbeta-independent mechanisms. Anti-osteoporotic. Inhibits adipogenic differentiation of bone marrow stromal cells (BMSC).

Supplier: VWR International
Description: Fluoropolymer tubing at less cost.
Supplier: Adipogen
Description: Potent and selective inhibitor of CDKs. More potent than olomoucine. Inhibits CDK1/cyclin B kinase (IC50 = 450 nM), CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM). Inhibits M phase promoting factor (MPF) kinase activity. Arrests human fibroblasts in G1 phase. Antitumor compound. Activates the mitogen-activated protein kinase pathway. Targets both the p53 and NF-kappaB pathways[10]. Has effects on calcium channel gating. Prevents DNA damage-induced cyclin A1 upregulation. Apoptosis inducer. As CYC202 in phase I clinical trials. Reviews.

Small Business Enterprise

Catalog Number: (470219-158)
Supplier: VWR International
Description: Conical bottom, polypropylene centrifuge tubes are supplied with cap.


Supplier: VWR International
Description: Ideal for drying gases, these polyethylene drying tubes have two push-on ends for easily filling with drying agents.
Supplier: Adipogen
Description: Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its 'high iron' conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo responsiveness. Binds IDH (isocitrate dehydrogenase), an excellent candidate for participating, along with aconitase and PKC, in an iron restriction signalosome. Contributes to heme biosynthesis which may account for its greater potency in restoring erythroid differentiation.

Small Business Enterprise

Supplier: VWR International
Description: Ideal for corrosive chemical transfer.

Supplier: VWR International
Description: General low pressure and temperature tubing.

Supplier: VWR International
Description: These tubes are made of optically clear PS and feature distinct molded graduations.
Supplier: VWR International
Description: Be more flexible.
Supplier: VWR International
Description: Disposable tubes feature plug-type polyethylene caps.
Supplier: VWR International
Description: High-performance and long-life tubing for high-purity applications.
Supplier: VWR International
Description: Microcentrifuge tubes, Cap, Natural, Nonsterile
Supplier: VWR International
Description: VWR® Screw-Cap Centrifuge tubes are supplied with 20 mm Ext.Ø.

CSA Certified

Supplier: VWR International
Description: FDA compliant for food contact.
Supplier: VWR International
Description: Ideal for general-purpose applications.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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