RO-3306 ≥95% (by NMR)

Supplier: ADIPOGEN CORP MS
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Synonyms: (Z)-5-(Quinolin-6-ylmethylene)-2-((thiophen-2-ylmethyl)amino)thiazol-4(5H)-one, (Z)-5-(Quinolin-6-ylmethylene)-2-[(thiophen-2-ylmethyl)amino]thiazol-4(5H)-one

AG-CR1-3515-M001 AG-CR1-3515-M005
102516-264EA 41.54 USD
102516-264 102516-266
RO-3306 ≥95% (by NMR)
RO-3306

Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M·Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards.

Formula: C₁₈H₁₃N₃OS₂
MW: 351.5 g/mol
Storage Temperature: Freezer
MDL Number: MFCD17392573
CAS Number: 872573-93-8

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Specification Test Results

Purity 95% (NMR)
Appearance/Color Brown solid.
Solubility Soluble in DMSO.

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