RO-3306 ≥95% (by NMR)
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
(Z)-5-(Quinolin-6-ylmethylene)-2-((thiophen-2-ylmethyl)amino)thiazol-4(5H)-one, (Z)-5-(Quinolin-6-ylmethylene)-2-[(thiophen-2-ylmethyl)amino]thiazol-4(5H)-one
Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M·Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards.
Formula:
C₁₈H₁₃N₃OS₂ MW: 351.5 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD17392573 CAS Number: 872573-93-8 |
Specification Test Results
Purity |
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Appearance/Color | Brown solid. |
Solubility | Soluble in DMSO. |
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