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Supplier: Matrix Scientific
Description: MF=C8H7CLO3 MW=186.60 CAS=10421-85-9 MDL=MFCD00084962 10G

Supplier: Thermo Scientific Chemicals
Description: 98%
Catalog Number: (10272-428)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R©1-3, GABAA R∂, GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.


Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 012673-25G , MDL Number: MFCD00064347

Supplier: MP Biomedicals
Description: DL-Thioctic Acid is a hydrogen transferrin cofactor.

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Supplier: Ambeed
Description: 5-Fluoro-DL-tryptophan 95%

New Product

Supplier: Ambeed
Description: Nɑ-Carbobenzoxy-DL-asparagine 98+%

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Supplier: Chem Impex International

Supplier: Ambeed
Description: DL-Tryptophan 98%

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Catalog Number: (10075-356)
Supplier: Prosci
Description: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.


Supplier: Thermo Scientific Chemicals
Description: 2-Phenylpropionic acid 98%

Supplier: Ambeed
Description: 2-Chloro-DL-phenylalanine 95%

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 037401-25G , MDL Number: MFCD00065398

Supplier: Matrix Scientific
Description: Ac-DL-Pro-OH

Supplier: Thermo Scientific Chemicals
Description: DL-Valine 98%, Extra Pure

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Supplier: ALADDIN SCIENTIFIC
Description: 3-(2-Pyridyl)-DL-alanine ≥98%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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