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You Searched For: 3-Ethyl-1-[2-(4-hydroxyphenyl)ethyl]urea


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Pneumocandin B0 98%

Supplier: Ambeed
Description: (10R,12S)-N((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-Amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2dihydroxy-2(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16], 98%, 135575-42-7, Size: 1MG

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2,2'-Methylenebis(6-tert-butyl-4-ethylphenol) ≥98.0%

Supplier: TCI America
Description: CAS Number: 88-24-4
MDL Number: MFCD00026296
Molecular Formula: C25H36O2
Molecular Weight: 368.56
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 125

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EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), No-Weigh™ Format, Pierce™

Catalog Number: (103523-940)
Supplier: Invitrogen
Description: Thermo Scientific Pierce EDC is a carboxyl- and amine-reactive zero-length crosslinker. EDC reacts with a carboxyl group first and forms an amine-reactive O-acylisourea intermediate that quickly reacts with an amino group to form an amide bond with release of an isourea by-product. The intermediate is unstable in aqueous solutions and so two-step conjugation procedures rely on N-hydroxysuccinimide (NHS) for stabilization. Failure to react with an amine will result in hydrolysis of the intermediate, regeneration of the carboxyl, and release of an N-substituted urea. A side reaction is the formation of an N-acylurea, which is usually restricted to carboxyls located in hydrophobic regions of proteins.

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Product Image-PI22980

EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), Pierce™

Supplier: Invitrogen
Description: Thermo Scientific Pierce EDC is a carboxyl- and amine-reactive zero-length crosslinker. EDC reacts with a carboxyl group first and forms an amine-reactive O-acylisourea intermediate that quickly reacts with an amino group to form an amide bond with release of an isourea by-product. The intermediate is unstable in aqueous solutions and so two-step conjugation procedures rely on N-hydroxysuccinimide (NHS) for stabilization. Failure to react with an amine will result in hydrolysis of the intermediate, regeneration of the carboxyl, and release of an N-substituted urea. A side reaction is the formation of an N-acylurea, which is usually restricted to carboxyls located in hydrophobic regions of proteins.

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Synephrine tartrate ≥98.0% (by HPLC, titration analysis)

Catalog Number: (TCS0233-025G)
Supplier: TCI America
Description: CAS Number: 16589-24-5 MDL Number: MFCD00151120 Molecular Formula: C9H13NO2 Molecular Weight: 484.50 Purity/Analysis Method: <gt/>98.0% (HPLC,T) Form: Crystal Color: White Melting point (°C): 184 Specific rotation [a]20/D: 13 deg (C=5, H2O)

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Image Unavailable-77245-564

2,2'-Methylenebis(6-tert-butyl-4-ethylphenol) 98%

Catalog Number: (77245-564)
Supplier: Ambeed
Description: 6,6'-Methylenebis(2-(tert-butyl)-4-ethylphenol), Purity: 98%, CAS Number: 88-24-4, Appearance: Form: Crystal - Powder/Colour: White - Very pale yellow, Storage: Inert atmosphere, Room Temperature, Size: 100g
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(R)-(−)-Phenylephrine hydrochloride ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 61-76-7
MDL Number: MFCD00012605
Molecular Formula: C9H13NO2
Molecular Weight: 203.67
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 143
Specific rotation [a]20/D: -45.5 deg (C=1, H2O)

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Image Unavailable-77602-454

Caspofungin acetate ≥98%

Supplier: Ambeed
Description: Caspofungin acetate ≥98%

New Product

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Pneumocandin B0 ≥96.0% (by HPLC)

Supplier: TCI America
Description: Pneumocandin B0, Purity: >96.0%(HPLC), CAS Number: 135575-42-7, Molecular Formula: C50H80N8O17, Molecular Weight: 1065.23, Size: 50MG

Product Image-76656-316

NS 1738 98%

Supplier: Ambeed
Description: 1-(5-Chloro-2-hydroxyphenyl)-3-(2-chloro-5-(trifluoromethyl)phenyl)urea, Purity: 98%, CAS Number: 501684-93-1, Appearance: solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100MG

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SNS-314 ≥95%

Supplier: Adipogen
Description: Aurora kinases constitute a family of serine-threonine kinases that are strongly associated with cancer. Aurora A and B are essential in mitosis. Perturbation of their activity leads to multiple defects in mitosis including aberrant centrosome duplication, misalignment of chromosomes, inhibition of cytokinesis, and disruption of the spindle checkpoint. The role of Aurora C is unclear; however, Aurora C can complement Aurora B kinase activity in mitosis. SNS-314 is an ATP-competitive, selective, and potent nanomolar inhibitor of aurora kinases in vitro. A cocrystal structure of SNS-314 with Aurora A confirms that SNS-314 engages the purine-binding pocket of Aurora. SNS-314 inhibits cellular proliferation in the HCT116 colorectal carcinoma cell line with an EC50 of ~5nM. Analysis of DNA content and indirect immunofluoresence demonstrates that SNS-314 induces defects in cytokinesis and spindle checkpoint that are consistent with Aurora kinase inhibition. Phosphorylation of Histone H3 on serine 10, a known Aurora B cellular target, is inhibited with an EC50 of ~9nM following treatment of cells with SNS-314. Administration of SNS-314 to HCT116 tumor bearing mice potently suppresses tumor growth. Analysis of SNS-314 treated tumors confirms that the anti-tumor activity is consistent with Aurora kinase inhibition. SNS-314 is a potent small-molecule inhibitor of Aurora kinase that is being developed as a novel anti-cancer therapeutic agent.

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PAP-AMC, Tyrosinase substrate ≥98% (by TLC)

Catalog Number: (76002-096)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for tyrosinase.
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NS 1738 ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: A selective positive allosteric modulator selective for α7 nicotinic acetylcholine receptors (α7 nAChR).

Image Unavailable-102843-138

3-Hydroxyphenylurea ≥97%

Supplier: Matrix Scientific
Description: 3-Hydroxyphenylurea ≥97%

Image Unavailable-102988-778

MCC950 sodium salt ≥98% (by HPLC)

Supplier: Adipogen
Description: Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin, but it does not inhibit NLRP1, NLRC4, AIM2, TLR2 signaling or priming of NLRP3. Prevents oligomerization of ASC in cells stimulated with LPS and nigericin. Active in vivo, blocking the production of IL-1beta and enhancing survival in mouse models of multiple sclerosis and cryopyrin-associated periodic syndrome (CAPS). Also active in ex vivo samples from individuals with Muckle-Wells syndrome. Potential therapeutic agent for NLRP3-associated syndromes, including autoinflammatory and autoimmune diseases.

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2-[2-Hydroxy-5-[2-(methacryloyloxy)ethyl]phenyl]-2H-benzotriazole ≥98.0%

Supplier: TCI America
Description: CAS Number: 96478-09-0
MDL Number: MFCD00213348
Molecular Formula: C18H17N3O3
Molecular Weight: 323.35
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 98

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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