You Searched For: (S)-Piperidine-3-carboxamide+hydrochloride


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Supplier: Matrix Scientific

SDS

Catalog Number: (101907-068)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 054323-500MG , MDL Number: MFCD14581673


Catalog Number: (101841-788)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 036641-500MG , MDL Number: MFCD09455694


Catalog Number: (101849-856)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 040616-500MG , MDL Number: MFCD12028322


Catalog Number: (101920-066)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 060455-500MG , MDL Number: MFCD13248778


Catalog Number: (101920-250)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 060566-500MG , MDL Number: MFCD16039373


Catalog Number: (101919-528)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 060163-500MG , MDL Number:


Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 052757-2.5G , MDL Number: MFCD11615743

Catalog Number: (101919-534)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 060166-500MG , MDL Number:


Catalog Number: (77692-768)
Supplier: LGC STANDARDS
Description: (RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide Hydrochloride, Mikromol, LGC Standards

New Product


Supplier: Ambeed
Description: AT7519 hydrochloride ≥98%

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 053531-2.5G , MDL Number: MFCD13562849

Supplier: MP Biomedicals
Description: Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization.
Supplier: Adipogen
Description: AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.

Supplier: Ambeed
Description: 4-(Ethylamino)piperidine-4-carboxamide 95%

Catalog Number: (101818-288)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 024543-500MG , MDL Number: MFCD09027738


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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