You Searched For: MP BIOMEDICALS (FKA ICN BIOMED

Supplier: MP Biomedicals

Description: Trypan blue is a blue acid dye with a strong affinity for cellulose containing substrates such as cotton; less affinity for proteinaceous materials.

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Supplier: MP Biomedicals

Description: PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

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Catalog Number: (IC7667494)

Supplier: MP Biomedicals

Description: A low-foaming, concentrated surfactant for use in automatic and mechanical washers

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Supplier: MP Biomedicals

Description: N-acetyl-DL-tryptophan, is used as stabilizer in the human blood-derived therapeutic products normal serum albumin and plasma protein fraction.

Supplier: MP Biomedicals

Description: Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. Con A exists as a dimer below pH 5.0 and and at pH >7 it exists as a tetramer. Con-A is not a glycoprotein. The monomeric molecular weight of Con-A is 25500. Con-A does not contain cysteine residues. Unlike most other lectins, Con-A is a metalloprotein and requires a transition metal ion, such as manganese, plus calcium ions for binding.

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Supplier: MP Biomedicals

Description: Citric acid acts as an iron chelator. It can support cholesterol/sterol, ubiquinone and isoprenoid biosynthesis in cell culture applications. In animals, citric acid improves the utilization of nutritional calcium. It is a useful buffer component.

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Supplier: MP Biomedicals

Description: Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

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Supplier: MP Biomedicals

Description: One unit will oxidize one µmole of protocatechuate to 3-carboxy-cis,cis-muconate per minute at pH 7.5 at 37 °C.

Supplier: MP Biomedicals

Description: Spectinomycin is an aminocyclitol antibiotic derived from <i>Streptomyces spectabilis</i>. It is active against gram-positive and gram-negative bacteria. Spectinomycin binds to the 30S subunit of bacterial ribosomes and suppresses protein synthesis.

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Supplier: MP Biomedicals

Description: CellMaxx™ Bovine Transferrin is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. Transferrin (HOLO) is an iron-rich product supplied as a heat-treated, lyophilised powder.

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Supplier: MP Biomedicals

Description: TMB is a chromogenic substrate for Horse Radish Peroxidase (HRP). MP Biolomedicals TMB Solution is a convenient, non toxic and ready to use stable chromogen solution suitable for peroxidase and pseudo-peroxidase reactions in ELISA, it provides consistent performance and sensitivity to deliver reproducible results

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Supplier: MP Biomedicals

Description: Sodium bisulfite, powder ACS

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Supplier: MP Biomedicals

Description: Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Other uses for poly-lysine have been reported as well:
• Conjugation to methotrexate for increased drug transport.
• Microencapsulation of islets.
• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.
• Immobilation of living cells in biocompatible semipermeable microcapsules.
• In the preparation of polycationic beads.
• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

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Supplier: MP Biomedicals

Description: Amino Acid Sequence:Glu-Cys-Gly, Glu-Cys-Gly [disulfide bridge: 2a-2b].

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Catalog Number: (IC642931)

Supplier: MP Biomedicals

Description: Mouse serum is used for blocking agents and controls in immunoassays

Catalog Number: (IC642921)

Supplier: MP Biomedicals

Description: Goat serum can be used in immunocytochemistry and blocking.