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Supplier: Bachem Americas
Description: This C-terminal fragment was shown to suppress the noradrenaline release from sympathetic nerve endings. It thereby mimics the effects of PYY and NPY at presynaptic (Y₂) receptors. The peptide was also able to compete with NPY for essentially all binding sites in rat brain.

Catalog Number: (N-1490.0025BA)
Supplier: Bachem Americas
Description: Sequence: Z-Pro-Pro-aldehyde-dimethyl acetal


Supplier: Bachem Americas
Description: Sequence: 6-Azido-hexanoic acid
Synonym(s): ε-Azidocaproic acid

Supplier: Bachem Americas
Description: Sequence: Z-Arg-pNA · HCl

Supplier: Bachem Americas
Description: Patented by Chromogenix AB, Sweden (CH 622 285). A highly specific substrate for human plasmin. For rat plasmin, Heinemann et al. determined a Km of 18.3 μM. Also cleaved by transmembrane tryptase (TMT).

Supplier: Bachem Americas
Description: Sequence: MeOSuc-Ala-Ala-Pro-Val-pNA

Supplier: Bachem Americas
Description: 6-FAM-D(OMe)E(OMe)VD(OMe)-FMK (methyl ester of FAM-DEVD-FMK) is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy.

Supplier: Bachem Americas
Description: AFP-pNA, substrate for prolyl tripeptidyl aminopeptidases from the periodontal pathogens Porphyromonas gingivalis and Prevotella nigrescens.

Supplier: Bachem Americas
Description: Sequence: H-Gly-Leu-OH

Supplier: Bachem Americas
Description: See also F-3260.

Supplier: Bachem Americas
Description: The FA-peptides M-1400 and M-1410 are common ACE substrates and thus filed in the corresponding product family. For our 3-(2-furyl)acryloyl-amino acids (FA-amino acids) and the labeling reagent FA-OSu (Q-1245), please see the Amino Acids section.

Catalog Number: (M-1330.0050BA)
Supplier: Bachem Americas
Description: See also F-3260.


Supplier: Bachem Americas
Description: Sequence: p-Hydroxyhippuryl-His-Leu-OH

Supplier: Bachem Americas
Description: Chocktide ((Trp⁴)-Kemptide) is readily phosphorylated by cAMP-dependent protein kinase. The phosphorylated peptide, in turn, is an effective substrate for phosphoprotein phosphatase. The changes in the substrate fluorescence intensity as a function of its phosphorylation state provide a sensitive assay of both enzyme activities.

Supplier: Bachem Americas
Description: Substrate V, Mca-RPPGFSAFK(Dnp), is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1) a membrane-bound zinc metallopeptidase that is related to neprilysin in amino acid sequence. The kcat/Km value for the hydrolysis by ECE-1 was 1.9 x 10⁷ M⁻¹s⁻¹ and 1.7 x 10⁶ M⁻¹s⁻¹ for the hydrolysis by neprilysin. This FRET substrate was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2. Mca-RPPGFSAFK(Dnp) has also found use as substrate for insulin-degrading enzyme (IDE) and ACE2.

Supplier: Bachem Americas
Description: Sequence: Boc-His(1-Boc)-OSu

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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