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Supplier: Bachem Americas
Description: The Glu³⁰ to Lys³³ lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date.

Catalog Number: (F-1535.0005BA)
Supplier: Bachem Americas
Description: Sequence: H-p-Fluoro-DL-Phe-OH


Supplier: Bachem Americas
Description: Fertilization-promoting peptide (FPP), a TRH analog, was previously purified and characterized from both rabbit prostate and human semen. Nanomolar concentrations of this peptide have been shown to enhance capacitation of mouse epididymal spermatozoa with a concomitant increase in fertilizing ability. It was also detected in the thyroid gland. According to a study of Nguyen et al. Pyr-Glu-Pro-NH₂ opposes the cholinergic effect of TRH in the mammalian CNS: Co-perfusion with an equivalent of TRH in the rat hippocampus resulted in a significant attenuation of TRH-induced acetylcholine release.

Supplier: Bachem Americas
Description: This fragment of myelin proteolipid protein is an encephalitogenic determinant, able to bind to diverse sets of T cell receptors.

Supplier: Bachem Americas
Description: Sequence: N-Me-Phe-OH

Supplier: Bachem Americas
Description: Sequence: H-Lys(Boc)-OH

Supplier: Bachem Americas
Description: Sequence: H-His(3-Me)-OH

Supplier: Bachem Americas
Description: Sequence: Tos-Pro-OH

Supplier: Bachem Americas
Description: Sequence: H-Asn(Trt)-OH

Supplier: Bachem Americas
Description: Sequence: H-Glu(OMe)-NH₂ · HCl

Supplier: Bachem Americas
Description: There is evidence that pretreatment of human polymorphonuclear neutrophils (PMN) with H-3030 results in the inhibition of TNF-α secretion, which indicates that this typical proinflammatory agent could play, at least at determined conditions, an antiinflammatory role. See also the Nle analog (H-3060).

Catalog Number: (H-3042.0005BA)
Supplier: Bachem Americas
Description: DPDMB, bombesin receptor antagonist with IC₅₀ values for cellular secretion and growth approaching the picomolar region.


Supplier: Bachem Americas
Description: Sequence: H-Arg(Pmc)-OtBu (free base)

Supplier: Bachem Americas
Description: C-ANF 4-23 binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture.

Supplier: Bachem Americas
Description: See also G-4745, H-3996, the branched substrates H-2416, and L-2070, and the product families 'Glutathione-Related Peptides' and 'Ophthalmic Acid'.

Supplier: Bachem Americas
Description: (Tyr³⁶)-pTHrP (1-36) has been used for radioiodination.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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