You Searched For: Wortmannin


24  results were found

SearchResultCount:"24"

Sort Results

List View Easy View

Rate These Search Results

Supplier: Thermo Scientific Chemicals
Description: Wortmannin 98%

Supplier: Adipogen
Description: Wortmannin is a potent anti-neutrophil agent with cardioprotective effects.

Small Business Enterprise

Supplier: Ambeed
Description: Wortmannin ≥98%

New Product

Supplier: Enzo Life Sciences
Description: PI3 kinase inhibitor

Catalog Number: (75790-024)
Supplier: Prosci
Description: Phosphatidylinositol 4-Kinase beta (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.


Supplier: Adipogen
Description: Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

Small Business Enterprise

Catalog Number: (102469-974)
Supplier: Affymetrix, Inc.
Description: 5 to 10^8 cells/test. Protocols: Use of Protocol A: Two-step protocol for intracellular (cytoplasmic) proteins is recommended and allows for the greatest flexibility for detection of surface and intracellular (cytoplasmic) proteins. Protocol C: Two-step protocol: Fixation/Methanol may be used and allows for the greatest discrimination of phospho-specific signaling between unstimulated and stimulated samples, but with limitations on the ability to stain specific surface proteins (refer to ""Clone Performance Following Fixation/Permeabilization"" located in the Best Protocols Section under the Resources tab online). Use of Protocol B: One-step protocol for intracellular (nuclear) proteins is not recommended. All Protocols can be found in the ""Staining Intracellular Antigens for Flow Cytometry Protocol"" located in the Best Protocols Section under the Resources tab online. eFluor®® 660 is a replacement for Alexa Fluor® 647. eFluor®® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Blocked

Catalog Number: (102469-972)
Supplier: Affymetrix, Inc.
Description: 5 to 10^8 cells/test. Protocols: Use of Protocol A: Two-step protocol for intracellular (cytoplasmic) proteins is recommended and allows for the greatest flexibility for detection of surface and intracellular (cytoplasmic) proteins. Protocol C: Two-step protocol: Fixation/Methanol may be used and allows for the greatest discrimination of phospho-specific signaling between unstimulated and stimulated samples, but with limitations on the ability to stain specific surface proteins (refer to ""Clone Performance Following Fixation/Permeabilization"" located in the Best Protocols Section under the Resources tab online). Use of Protocol B: One-step protocol for intracellular (nuclear) proteins is not recommended. All Protocols can be found in the ""Staining Intracellular Antigens for Flow Cytometry Protocol"" located in the Best Protocols Section under the Resources tab online. eFluor®® 660 is a replacement for Alexa Fluor® 647. eFluor®® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Blocked

Catalog Number: (77561-452)
Supplier: Sino Biological
Description: WORTMANNIN 1MG

New Product


Catalog Number: (77871-496)
Supplier: Ambeed
Description: WORTMANNIN 5MG

New Product


Catalog Number: (80055-508)
Supplier: MilliporeSigma
Description: WORTMANNIN 1MG

Catalog Number: (101755-962)
Supplier: Cell Signaling Technology
Description: 9951S WORTMANNIN-1 MG

Blocked

Catalog Number: (220232-867)
Supplier: Sigma Aldrich
Description: WORTMANNIN, READY MADE SOLUTIO

Blocked

Catalog Number: (220230-241)
Supplier: Sigma Aldrich
Description: WORTMANNIN

Blocked

Catalog Number: (220230-242)
Supplier: Sigma Aldrich
Description: WORTMANNIN

Blocked

Catalog Number: (77561-454)
Supplier: Sino Biological
Description: WORTMANNIN 5MG

New Product


Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
1 - 16 of 24
no targeter for Bottom