You Searched For: Thiophen-3-amine+oxalate(1:x)


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Supplier: Ambeed
Description: Thiophen-3-amine oxalate(1:x) 97%

Catalog Number: (76983-346)
Supplier: Ambeed
Description: 4,5,6,7-Tetrahydrobenzo[b]thiophen-2-amine oxalate, Purity: 95%, CAS number: 1216924-54-7, Appearance: White to yellow powder or crystals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100MG


Supplier: Ambeed
Description: (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate, Purity: 95%, CAS number: 132335-47-8, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 10G

Catalog Number: (ALA174452250MG)
Supplier: ALADDIN SCIENTIFIC CORPORATION
Description: 3-(Aminomethyl)oxetan-3-amine oxalic acid ≥97%

New Product


Supplier: Matrix Scientific
Description: MF=C7H11N3O4 MW=201.18 CAS=1010800-27-7 MDL=MFCD11114053 5G

Catalog Number: (101849-356)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 040360-500MG , MDL Number: MFCD09839057


Catalog Number: (101919-672)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 060235-500MG , MDL Number: MFCD18071174


Catalog Number: (101907-940)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 054620-500MG , MDL Number: MFCD13248815


Catalog Number: (101189-712)
Supplier: BioVendor
Description: Uromodulin (Tamm-Horsfall protein, UMOD) is approx. 85-kDa glycoprotein that is produced in the thick ascending limb of Henle´s loop and early distal convoluted tubules of the nephron. It is a transmembrane protein, which is secreted into the urine through proteolytic cleavage of the glycosylphosphatidylinositol (GPI) anchor. It belongs to the GPI family. Healthy individuals excrete tens of miligrams of uromodulin per day, making in the most abundant protein in the urine. Uromodulin modulates cell adhesion and signal transduction by interacting with cytokines and it inhibits the aggregation of calcium crystals. By reducing calcium oxalate precipitation, uromodulin plays a protective role with respect to renal stone formation as demonstrated by recent studies on THP- deficient mice prone to nephrolithiasis. THP acts as a host defense factor against urinary tract infections induced by uropathogens such as Esherichia coli, Staphylococcus saphrophyticus, Proteus mirabilis and Klebsiela pneumonie. Uromodulin binds to type 1 fimbriae of Escherichia coli and thereby blocks colonization of urothelial cells. Tamm-Horsfall protein interacts with other molecules and cells including IL-1, IL-2, TNF, IgG, neuthrophils, lymphocytes and monocytes. Binding of uromodulin to neutrophils induces synthesis of IL-8, provokes the respiratory burst and degranulation and stimulates chemotaxis and phagocytosis. Recently, genome-wide association studies identified uromodulin as a risk factor for chronic kidney disease and hypertension. Mutations in the Uromodulin gene are associated with three autosomal dominant tubulo-interstitial nephropathies such as familial juvenile hyperuricemic nephropathy (FJHN), medullary cystic kidney disease (MCKD2) and glomerulocystic kidney disease (GCKD). These disorders are characterized by juvenile onset of hyperuricemia, gout and progressive renal failure.


Catalog Number: (102552-968)
Supplier: BioVendor
Description: Uromodulin (Tamm-Horsfall protein, UMOD) is approx. 85-kDa glycoprotein that is produced in the thick ascending limb of Henle´s loop and early distal convoluted tubules of the nephron. It is a transmembrane protein, which is secreted into the urine through proteolytic cleavage of the glycosylphosphatidylinositol (GPI) anchor. It belongs to the GPI family. Healthy individuals excrete tens of miligrams of uromodulin per day, making in the most abundant protein in the urine. Uromodulin modulates cell adhesion and signal transduction by interacting with cytokines and it inhibits the aggregation of calcium crystals. By reducing calcium oxalate precipitation, uromodulin plays a protective role with respect to renal stone formation as demonstrated by recent studies on THP- deficient mice prone to nephrolithiasis. THP acts as a host defense factor against urinary tract infections induced by uropathogens such as Esherichia coli, Staphylococcus saphrophyticus, Proteus mirabilis and Klebsiela pneumonie. Uromodulin binds to type 1 fimbriae of Escherichia coli and thereby blocks colonization of urothelial cells. Tamm-Horsfall protein interacts with other molecules and cells including IL-1, IL-2, TNF, IgG, neuthrophils, lymphocytes and monocytes. Binding of uromodulin to neutrophils induces synthesis of IL-8, provokes the respiratory burst and degranulation and stimulates chemotaxis and phagocytosis. Recently, genome-wide association studies identified uromodulin as a risk factor for chronic kidney disease and hypertension. Mutations in the Uromodulin gene are associated with three autosomal dominant tubulo-interstitial nephropathies such as familial juvenile hyperuricemic nephropathy (FJHN), medullary cystic kidney disease (MCKD2) and glomerulocystic kidney disease (GCKD). These disorders are characterized by juvenile onset of hyperuricemia, gout and progressive renal failure.


Catalog Number: (77692-725)
Supplier: LGC STANDARDS
Description: 3-[(1RS)-5-Chloro-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl]-N,N-dimethylpropan-1-amine Oxalate, Mikromol, LGC Standards

New Product


Catalog Number: (102899-962)
Supplier: Matrix Scientific

SDS


Catalog Number: (101802-522)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 012411-500MG , MDL Number: MFCD05656875


Catalog Number: (101842-480)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 036994-500MG , MDL Number: MFCD12027029


Catalog Number: (101841-868)
Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 036681-500MG , MDL Number: MFCD12026964


Supplier: TCI America
Description: Dibenzo[b,d]thiophen-2-amine ≥98.0% (by GC, titration analysis)

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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