You Searched For: ROS+Brite\u2122

Catalog Number: (10110-502)

Supplier: Prosci

Description: Suppression of the expression of TRAP1 in mitochondria might play an important role in the induction of apoptosis caused via formation of ROS.

Supplier: Ambeed

Description: N-(4-(4-Isopropoxybenzyl)phenyl)-4,5-dihydro-1H-imidazol-2-amine, Purity: 97%, CAS Number: 221529-58-4, Appearance: Yellow solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 100mg

Catalog Number: (77439-324)

Supplier: Bioss

Description: Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.

Catalog Number: (10119-426)

Supplier: Gold Standard Diagnostics

Description: Gold Standard Diagnostics offers a comprehensive menu of ELISA assays for Infectious Disease & Autoimmune diagnostic testing

SDS

Catalog Number: (102515-232)

Supplier: Adipogen

Description: Glutathione peroxidase 1 (GPX1) is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.

Catalog Number: (10431-492)

Supplier: Bioss

Description: May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).

Catalog Number: (76746-504)

Supplier: ANTIBODIES.COM LLC

Description: Rat NT-ProANP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rat NT-ProANP in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Adipogen

Description: Bisindoylmaleimide X is a potent and selective protein kinase C (PKC) inhibitor (IC(50) of 15nM for rat brain PKC). It also inhibits Fas-mediated apoptosis and T cell-mediated autoimmune diseases.

Catalog Number: (102988-248)

Supplier: Adipogen

Description: A-Type proanthocyanidine. Selective cytotoxic agent. Potent antioxidant. Lipid peroxidation inhibitor. Antidiabetic, with similar effects to insulin activity in adipogenesis. Free radical scavenger. Antithrombotic. Inhibits platelet aggregation. Apoptosis inhibitor. Reduces intracellular Ca(2+) overload and ROS production. Antibacterial. Cyclooxygenase-2 (COX-2) inhibitor in vitro. LDL oxidation inhibitor.

Supplier: Bachem Americas

Description: Sequence: 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
Synonym(s): Edelfosine#ALP#ET 18-OCH3#ET-18-OMe#NSC 324368#NSC 343649#Ro 14-5243

Supplier: Adipogen

Description: Negative control for protein kinase C (PKC) inhibitors. S6K inhibitor. Necrosis inhibitor.

Catalog Number: (76109-374)

Supplier: Bioss

Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.

Catalog Number: (10320-776)

Supplier: Bioss

Description: LTK is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Catalog Number: (10320-770)

Supplier: Bioss

Description: LTK is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Catalog Number: (77440-570)

Supplier: Bioss

Description: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Supplier: Adipogen

Description: Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion inhibition. Collagen-induced platelet aggregation inhibitor. Antioxidant agent that enhances osseointegration by decreasing the level of ROS and having a potentially synergistic effect on osteoblast differentiation. Proteasome inhibitor.