You Searched For: Puromycin+dihydrochloride

Catalog Number: (101973-614)

Supplier: MORAVEK BIOCHEMICALS MS

Description: Puromycin dihydrochloride, [8-3H(N)] ≥97% (by HPLC), MORpure™

Supplier: Thermo Scientific Chemicals

Description: Puromycin dihydrochloride hydrate 99%

Supplier: Enzo Life Sciences

Description: Inhibits protein synthesis

Certificates

Supplier: MP Biomedicals

Description: Puromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis and 4) antitrypanosome activity.
Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from Streptomyces alboniger. It is a broad spectrum antibiotic with antitumor activity, as an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Supplier: Adipogen

Description: Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems. It allows selection for cells that contain the resistance gene puromycin N-acetyl-transferase (PAC). Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/ml. Puromycin-resistant stable mammalian cell lines can be generated in less than one week.

Catalog Number: (10766-886)

Supplier: Mirus Bio

Description: Puromycin antibiotic ensures effective positive selection of cells expressing the puromycin-N-acetyltransferase (<i>pac</i>) gene.

SDS

Supplier: Ambeed

Description: Puromycin dihydrochloride ≥98%

New Product

Catalog Number: (62111-170)

Supplier: Corning

Description: Puromycin dihydrochloride is a nucleoside antibiotic and protein synthesis inhibitor.

Certificates

Supplier: Thermo Scientific Chemicals

Description: Causes premature chain termination in protein synthesis

SDS Certificates

Supplier: MP Biomedicals

Description: Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from <i>Streptomyces alboniger</i>.

SDS

Catalog Number: (AAJ67236-8EQ)

Supplier: Thermo Scientific Chemicals

Description: Puromycin is also used as a substrate of Mdr-1. It is widely used in cell culture applications. It also induces apoptosis which was found as parallel apoptosis caused by deprivation of neuronal growth factor (NGF) in developing chick sympathetic neurons. Shown to arrest cells in G2/M phase. Puromycin is an inhibitor of CD13 and DPP7.

SDS Certificates

Catalog Number: (89156-360)

Supplier: Enzo Life Sciences

Description: A puromycin analog which does not inhibit protein synthesis or induce apoptosis

Supplier: Thermo Scientific Chemicals

Description: A puromycin aminonucleoside useful in the study of human glomerular disease.

Certificates

Catalog Number: (103286-002)

Supplier: Novus Biologicals

Description: The Puromycin-sensitive aminopeptidase / NPEPPS Antibody from Novus Biologicals is a rabbit polyclonal antibody to Puromycin-sensitive aminopeptidase / NPEPPS. This antibody reacts with human. The Puromycin-sensitive aminopeptidase / NPEPPS Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.

Catalog Number: (77518-380)

Supplier: AFG BIOSCIENCE LLC

Description: Human PSA (Puromycin Sensitive Aminopeptidase) ELISA Kit

New Product

Catalog Number: (10108-374)

Supplier: Prosci

Description: EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).