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Poly-(L-lysine) 95%

Supplier: Ambeed
Description: Poly-(L-lysine) 95%

New Product

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ε-Poly-L-lysine 97%, Technical Grade

Supplier: Ambeed
Description: ε-Poly-L-lysine 97%, Technical Grade

New Product

Product Image-103701-194

Poly-D-lysine 0,1 mg/mL

Catalog Number: (103701-194)
Supplier: ADVANCED BIOMATRIX, INC. MS
Description: Poly-D-Lysine is a synthetic amino acid chain that is positively charged and widely used as a coating to enhance cell attachment and adhesion to both plasticware and glass surfaces. This molecule is resistant to enzymatic degradation and has been used to culture a wide variety of cell types.
The molecular weight of Poly-D-Lysine can vary significantly with lower molecular weight (30,000 Da) being less viscous and higher molecular weight (>300,000 Da) having more binding sites per molecule. This product’s molecular weight ranges from 70,000 to 150,000 Da yielding a solution viscosity for easy handling while providing sufficient binding sites for cell attachment.

Poly-D-Lysine surface coatings are designed to improve cell attachment, growth and differentiation of many cell types. Coated surfaces will often improve cell attachment in reduced or serum-free conditions. Poly-D-Lysine is supplied in a sterile 5 mg package size.
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Poly-D-lysine hydrobromide, white powder

Supplier: MP Biomedicals
Description: Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Other uses for poly-lysine have been reported as well:
• Conjugation to methotrexate for increased drug transport.
• Microencapsulation of islets.
• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.
• Immobilation of living cells in biocompatible semipermeable microcapsules.
• In the preparation of polycationic beads.
• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

SDS Certificates

Image Unavailable-IC10269480

Poly-D-lysine hydrobromide (synthetic), white powder

Supplier: MP Biomedicals
Description: Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein.

SDS

Product Image-103701-192

Poly-L-Lysine

Catalog Number: (103701-192)
Supplier: ADVANCED BIOMATRIX, INC. MS
Description: Poly-L-Lysine is a synthetic amino acid chain that is positively charged having one hydrobromide per unit of Lysine. Poly-L-Lysine is widely used as a coating to enhance cell attachment and adhesion to both plasticware and glass surfaces. This molecule has been used to culture a wide variety of cell types. Certain cell types secrete proteases, which can digest Poly-L-Lysine. For those cell types, Poly-D-Lysine 000 Da) being less viscous and higher molecular weight (>300,000 Da) having more binding sites per molecule. This product’s molecular weight ranges from 70,000 to 150,000 Da yielding a solution viscosity for easy handling while providing sufficient binding sites for cell attachment.

Poly-L-Lysine surface coatings are designed to improve cell attachment, growth and differentiation of many cell types. Coated surfaces will often improve cell attachment in reduced or serum-free conditions. This product is supplied in a sterile 50 ml package size at a concentration of 0.1 mg/ml.
Product Image-62406-040

Corning® BioCoat® Poly-D-Lysine Culture Dishes, Corning

Supplier: Corning
Description: Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Certificates Environmentally Preferable

Product Image-BD354086

Corning® BioCoat® Poly-D-Lysine Coverslips, Corning

Catalog Number: (BD354086)
Supplier: Corning
Description: Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Certificates Environmentally Preferable


Product Image-62406-350

Corning® BioCoat® Poly-D-Lysine Microplates, Corning

Supplier: Corning
Description: Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Certificates Environmentally Preferable

Product Image-76076-740

Unifrost™ Adhesive Microscope Slides, Azer Scientific

Catalog Number: (76076-740)
Supplier: Azer Scientific Inc.
Description: These adhesive microscope slides are coated with Poly-L-Lysine.

Certificates


Product Image-62405-890

Corning® BioCoat® Poly-D-Lysine Culture Slides, Corning

Supplier: Corning
Description: Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Certificates Environmentally Preferable

Image Unavailable-76204-002

Poly-L-lysine hydrobromide, MP Biomedicals

Catalog Number: (76204-002)
Supplier: MP Biomedicals
Description: Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.
Product Image-100490-312

Poly-L-Lysine Coated and Silane Treated Microscope Slide, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: Premium glass slides with a frosted end. These slides improve the adhesion of tissues to the slide. Available pre-coated with either Poly-L-Lysine or Silane (aminoalkysilane).

Minority or Woman-Owned Business Enterprise

Product Image-87001-894

Poly (l-lysine hydrobromide)

Catalog Number: (87001-894)
Supplier: Polysciences Inc
Description: Cationic polymer

Small Business Enterprise Product available on GSA Advantage®


Product Image-BD354087

Corning® BioCoat® Poly-D-Lysine/Laminin German Glass Coverslip, 12 mm, Corning

Catalog Number: (BD354087)
Supplier: Corning
Description: Corning® BioCoat™ Poly-D-Lysine/Laminin 12mm #1 German Glass coverslip with a uniform application of poly-D-lysine and laminin. Bulk packed, 80/case. Corning BioCoat products are an ideal solution for enhanced cell attachment and growth of a variety of primary cells and transformed cells in serum-free or serum-containing cultures. Corning offers custom coating capabilities.

Certificates Environmentally Preferable Product available on GSA Advantage®


Product Image-12777-084

Corning® BioCoat® Poly-D-Lysine Flasks, Corning

Supplier: Corning
Description: Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Certificates Environmentally Preferable

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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