You Searched For: Paxilline


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Supplier: Enzo Life Sciences
Description: K+ channel blocker

Catalog Number: (AAJ61341-LB0)
Supplier: Thermo Scientific Chemicals
Description: Potent blocker of high-conductance calcium-activated potassium (BKCa) channels

Supplier: Adipogen
Description: Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death.

Catalog Number: (103430-842)
Supplier: Affymetrix, Inc.
Description: This Antibody targets Paxillin in IHC (P) and WB applications and shows reactivity with Human samples. The immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 86 and 591 of Paxillin. Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

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Catalog Number: (76708-946)
Supplier: AFG BIOSCIENCE LLC
Description: Human Paxillin(Pax) ELISA Kit


Catalog Number: (77050-128)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to Paxillin (phospho Tyr88) for WB and ELISA with samples derived from Human.


Catalog Number: (77213-512)
Supplier: ANTIBODIES.COM LLC
Description: Human Paxillin ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Paxillin in serum, plasma, and other biological fluids.


Catalog Number: (77519-984)
Supplier: AFG BIOSCIENCE LLC
Description: Mouse Pax (Paxillin) ELISA Kit

New Product


Catalog Number: (77513-784)
Supplier: AFG BIOSCIENCE LLC
Description: Human Pax (Paxillin) ELISA Kit

New Product


Catalog Number: (103488-566)
Supplier: Affymetrix, Inc.
Description: MA5-13356 targets Paxillin in IF, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples. The MA5-13356 immunogen is purified recombinant full-length human paxillin protein. Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Blocked

Catalog Number: (77053-806)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to Paxillin for WB and ELISA with samples derived from Human, Mouse and Rat.


Catalog Number: (10206-028)
Supplier: Boster Biological Technology
Description: Mouse IgG monoclonal antibody for Paxillin, paxillin (PXN) detection. Tested with WB, ICC in Human;mouse;rat;chicken. No cross reactivity with other proteins.


Catalog Number: (77049-860)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to Paxillin for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.


Catalog Number: (75930-740)
Supplier: Rockland Immunochemical
Description: The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. This antibody is suitable for researchers interested in growth factors and signal trasduction.


Catalog Number: (89316-548)
Supplier: Genetex
Description: Mouse monoclonal [PXC - 10] to Paxillin


Catalog Number: (102149-576)
Supplier: Novus Biologicals
Description: Paxillin Overexpression Lysate (Adult Normal)


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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