paxilline
Supplier: ADIPOGEN CORP MS
AG-CN2-0167-M001
AG-CN2-0167-M005
102988-126EA
62.31
USD
102988-126
102988-128
paxilline
Paxilline
Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death.
Formula:
C₂₇H₃₃NO₄ |
MDL Number:
MFCD00083464 CAS Number: 57186-25-1 |
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