paxilline

Supplier: ADIPOGEN CORP MS

AG-CN2-0167-M001 AG-CN2-0167-M005
102988-126EA 62.31 USD
102988-126 102988-128
paxilline
Paxilline

Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death.

Formula: C₂₇H₃₃NO₄
MDL Number: MFCD00083464
CAS Number: 57186-25-1

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