Paxilline ≥97% (by HPLC)
Supplier: Enzo Life Sciences
BML-KC155-0005
BML-KC155-0025
89160-224EA
163.5
USD
89160-224
89160-226
Paxilline ≥97% (by HPLC)
Paxilline
K+ channel blocker
Paxilline is an indole alkaloid isolated from Penicillium paxilli. It is a selective and reversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (70% block at 10 nM). In neutrophils, Paxilline blockage of BKCa channels decreased the alkalinization of phagocytic vacuoles and inhibited the microbicidal process. Inhibitor of the cerebellar inositol 1,4,5-triphosphate (InsP(3)) receptor.
Formula:
C₂₇H₃₃NO₄ |
MDL Number:
MFCD00083464 CAS Number: 57186-25-1 |
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