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Catalog Number: (TS351460075)
Supplier: Thermo Scientific Chemicals
Description: Packaged in 0.75 ml ampoules

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Supplier: Adipogen
Description: Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice.

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00003286
Supplier: Adipogen
Description: A phosphine with enhanced solubility in solvents. Phosphines are used as ligands for many metal complexes.

Catalog Number: (102988-916)
Supplier: Adipogen
Description: (+)-Flavipucine is an anti-bacterial and anti-fungal compound.


Supplier: Adipogen
Description: Selective N- and P/Q-type Ca2+-channel agonist. These Ca2+-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.

Supplier: Adipogen
Description: Stable analog of pifithrin-alpha. p53 inhibitor.

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Supplier: Adipogen
Description: Quorum sensing agent.

Catalog Number: (102516-242)
Supplier: Adipogen
Description: Nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Shows potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity. Anti-aggregating agent.

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Supplier: Adipogen
Description: IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. NLRP3 inflammasome inhibitor. Reduces ATPase activity of the NLRP3 inflammasome. Inhibits platelet aggregation.

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Catalog Number: (102989-058)
Supplier: Adipogen
Description: Mycotoxin. Phytotoxic and cytotoxic agent. Immunosuppressive activity. Affects chromosome congression and spindle microtubule organization in PtK1 cells. Actin and myosin inhibitor.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00044563
Supplier: Enzo Life Sciences
Description: Nitric oxide (NO) donor.

Supplier: Adipogen
Description: Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency.

Supplier: Adipogen
Description: Building block for synthesis.

Catalog Number: (AA42280-06)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00037106

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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