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Supplier: Adipogen
Description: Merck 5, also known as Pyridone 6, is a potent and reversible ATP-competitive inhibitor of the JAK kinases (JAK1, JAK2, JAK3, and Tyk2) with IC(50) values in the low anomolar range. At higher values (IC(50) <gt/>100nM) Merck 5 also can inhibit ERK kinase family and appear to block IL-2 and IL-4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5. In research comparing Merck 5 (Pyridone 6) to the Jak inhibitor AG490, Merck 5 demonstrated much lower effective drug concentrations and faster kinetics and appear to be a more sensitive and specific inhibitor of JAK-STAT3 activity compared with AG490 and potently inhibited the growth of primary myeloma cells and myeloma-derived cell lines grown on bone marrow-derived stromal cells .

Supplier: Ambeed
Description: Merck-5 ≥98%

New Product

Supplier: BeanTown Chemical
Description: Molecular formula: (C₁₂H₁₈O₉)n
Merck number: 14,184
EC number: 232-658-1

SDS

Catalog Number: (EM1.40140.0001)
Supplier: MilliporeSigma

SDS


Supplier: MilliporeSigma
Description: Supelco® Solvent Pumps, Merck

Supplier: BeanTown Chemical
Description: EC No: 240-140-1
RTECS: LJ8080000
Molecular formula: C₃₄H₃₂ClFeN₄O₄
MW: 651.95
Merck Number: 14,4644

SDS

Supplier: MilliporeSigma
Description: Merck's standardised and modified silica gels that are available in many granulations and supplied from one single source, dedicated to chromatography.
Supplier: MilliporeSigma

Supplier: MilliporeSigma
Description: LiChrospher® is Merck's reliable and versatile traditionally produced spherical silica.

Supplier: MilliporeSigma
Description: LiChrosorb® Si 100 is a reliable irregular shaped silica sorbent with a pore diameter of 100 Å for normal phase chromatography.

SDS

Supplier: BeanTown Chemical
Description: EC No: 232-555-1
RTECS: FI3519500
Melting Point: 280 °C (decomposes)
Sensitivity: Hygroscopic
Merck Number: 14,1883

SDS

Catalog Number: (EM1.14821.0002)
Supplier: MilliporeSigma
Description: <B>All Spectroquant® test kits</B> can be used with the <B>Prove</B> range of spectrophotometers and Nova 60/60A instruments. Tests can be used not only on photometers and spectrophotometer from Merck, but also on photometers and spectrophotometers from other suppliers (programming details available on request).

SDS


Supplier: MilliporeSigma

Catalog Number: (EM1.07739.1000)
Supplier: MilliporeSigma
Description: Standardized sorbents ensure reliable results every time

Supplier: MilliporeSigma
Description: Standardized sorbents ensure reliable results every time

Catalog Number: (EM1.01090.2500)
Supplier: MilliporeSigma
Description: Standardized sorbents ensure reliable results every time


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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