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Ganglioside GM1 sodium salt ≥98% (by TLC)

Supplier: Adipogen
Description: Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM1 is a major sialoglycolipid of neuronal membranes that modulates calcium homeostasis and which is important for neuronal plasticity and repair mechanisms. It binds to cholera toxin B subunit, resulting in stimulation of adenylyl cyclase in a wide variety of cell types. After cholera toxin binds to membrane associated Monosialoganglioside GM1, the A subunit of cholera toxin is translocated to the cell interior, where it catalyzes the ADP ribosylation of the membrane associated Gs subunit of adenylyl cyclase. In addition, binding of cholera toxin to monosialoganglioside GM1 causes translocation of NF-kappaB and activation of dendritic cells. E. coli heat-labile enterotoxin (LT) is structurally and functionally similar to cholera toxin and binds GM1 as well. GM1 has also been shown to improve Parkinson's disease symptoms and slow it's progression.

Product Image-89148-634

Bovine Native Ganglioside GM1 . Sodium Salt (from Brain)

Supplier: Enzo Life Sciences
Description: Specific receptor for cholera toxin.

Image Unavailable-102988-410

Ganglioside GD1a disodium salt ≥98% (by TLC)

Supplier: Adipogen
Description: Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1a is the major ganglioside of the nervous system. It is converted to GM1 by bacterial, viral and mammalian sialidases. It is a differentiation marker for cell growth.

Image Unavailable-TCA2505-VIAL

Anti-GM1 Mouse Monoclonal Antibody [clone: GMB16]

Catalog Number: (TCA2505-VIAL)
Supplier: TCI America
Description: Purified mouse monoclonal antibody/IgM, κ-chain

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Image Unavailable-102988-428

Asialo-Ganglioside GM1 ≥98% (by TLC)

Supplier: Adipogen
Description: Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Removing the sialic acid from monosialoganglioside GM1 inhibits its ability to bind cholera toxin. Asialo-ganglioside GM1 does not block the binding of cholera toxin to cellular GM1.

Image Unavailable-10333-052

Anti-GPER1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10333-052)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
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Ganglioside GM2 sodium salt ≥98% (by TLC)

Catalog Number: (102988-404)
Supplier: Adipogen
Description: Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM2 is a very minor component of the nervous system, but it is accumulated in brains from Tay-Sachs and Sandhoff disease patients, due to genetic defect of lysosomal beta-hexosaminidase.
Product Image-77510-800

Human Anti-GM1 (Anti-Ganglioside Antibody) ELISA Kit

Catalog Number: (77510-800)
Supplier: AFG BIOSCIENCE LLC
Description: Human Anti-GM1 (Anti-Ganglioside Antibody) ELISA Kit

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Image Unavailable-10333-056

Anti-GPER1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10333-056)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Image Unavailable-76098-756

Anti-ganglioside GM1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76098-756)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Image Unavailable-10333-046

Anti-GPER1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (10333-046)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Image Unavailable-10333-060

Anti-GPER1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10333-060)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Image Unavailable-10333-042

Anti-GPER1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (10333-042)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Image Unavailable-10333-048

Anti-GPER1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (10333-048)
Supplier: Bioss
Description: A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
Product Image-89148-688

GM1 Pentasaccharide . sodium salt

Catalog Number: (89148-688)
Supplier: Enzo Life Sciences
Description: Semisynthetic (from GM1).
Product Image-76699-106

Human Aniti-Ganglioside Antibody(GM1) ELISA Kit

Catalog Number: (76699-106)
Supplier: AFG BIOSCIENCE LLC
Description: Human Aniti-Ganglioside Antibody(GM1) ELISA Kit
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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